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Tumor angiogenesis in breast cancer: Its importance as a prognostic indicator and the association with vascular endothelial growth factor expression
TLDR
It was concluded that MVD is a potent prognostic indicator in primary breast cancer and it was suggested that VEGF plays crucial roles in the promotion of angiogenesis in breast cancer. Expand
Clinicopathologic Characteristics and Prognosis of Breast Cancer Patients Associated with Pregnancy and Lactation: Analysis of Case‐Control Study in Japan
TLDR
Most of the patients with breast cancer diagnosed during pregnancy and lactation are in a more advanced stage because of a delay in detection and diagnosis, and hence have unfavorable prognosis, and it is important to diagnose and treat early for improvement of prognosis. Expand
Tissue factor expression in breast cancer tissues: its correlation with prognosis and plasma concentration
TLDR
The data show that plasma TF concentration reflects tissue TF expression and tumour TF expression can provide some predictive value for prognosis and distant metastasis, which indicates the importance of TF function in tumour progression. Expand
Combined tamoxifen and luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist alone in premenopausal advanced breast cancer: a meta-analysis of four randomized trials.
TLDR
If a premenopausal woman with advanced breast cancer is thought to be suitable for endocrine treatment, it is proposed that the combination of a LHRH agonist plus tamoxifen be considered as the new standard treatment. Expand
Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma.
TLDR
Levels of VEGF in tumor tissue samples are found to be prognostic for both relapse-free and overall survival in univariate and multivariate analyses, and all four P values < .001 were found. Expand
Association of Vascular Endothelial Growth Factor Expression with Tumor Angiogenesis and with Early Relapse in Primary Breast Cancer
TLDR
It was suggested that the expression of VEGF is closely associated with the promotion of angiogenesis and with early relapse in primary breast cancer. Expand
Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients.
TLDR
It was concluded that VEGF was detectable in normal sera, and its level was increased in some populations of cancer patients, particularly for solid tumors. Expand
Meta‐analysis of trials comparing toremifene with tamoxifen and factors predicting outcome of antiestrogen therapy in postmenopausal women with breast cancer
TLDR
TOR 60 mg/day and TAM are equally effective and well tolerated in the treatment of advanced breast cancer in postmenopausal women and prediction of survival may be predicted based on patient characteristics and on the initial response to the treatment. Expand
Tumor angiogenesis is an independent prognostic indicator in primary breast carcinoma
TLDR
Breakdown analysis stratified by nodal status showed that the vessel density was a significant prognostic indicator in node‐negative and node‐positive patients and Multivariate analysis indicated that the vessels density is an independent prognostic indicators in primary breast‐cancer patients. Expand
Vascular endothelial growth factor and platelet-derived endothelial cell growth factor are frequently coexpressed in highly vascularized human breast cancer.
TLDR
It was found that VEGF and PD-ECGF were frequently coexpressed in highly vascularized tumors with high microvessel counts, and it was suggested that V EGF andPD- ECGF might cooperatively function in the neovascularization of human breast cancer. Expand
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