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Drug Resistance Mutations for Surveillance of Transmitted HIV-1 Drug-Resistance: 2009 Update
Programs that monitor local, national, and regional levels of transmitted HIV-1 drug resistance inform treatment guidelines and provide feedback on the success of HIV-1 treatment and prevention… Expand
Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters
- N. Wolfe, W. Heneine, +12 authors W. Switzer
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 23 May 2005
The human T-lymphotropic viruses (HTLVs) types 1 and 2 originated independently and are related to distinct lineages of simian T-lymphotropic viruses (STLV-1 and STLV-2, respectively). These facts,… Expand
Naturally acquired simian retrovirus infections in central African hunters
BACKGROUND Hunting and butchering of wild non-human primates infected with simian immunodeficiency virus (SIV) is thought to have sparked the HIV pandemic. Although SIV and other primate retroviruses… Expand
Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis.
- M. Witvrouw, C. Pannecouque, W. Switzer, T. Folks, E. de Clercq, W. Heneine
- Medicine, Biology
- Antiviral therapy
- 1 February 2004
Limited information is available on the activity of antiretroviral drugs against human immunodeficiency virus type 2 (HIV-2) and simian immunodeficiency virus (SIV) strains to guide their use in… Expand
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein.
- N. Laguette, Nadia Rahm, +10 authors M. Benkirane
- Biology, Medicine
- Cell host & microbe
- 16 February 2012
SAMHD1 has recently been identified as an HIV-1 restriction factor operating in myeloid cells. As a countermeasure, the Vpx accessory protein from HIV-2 and certain lineages of SIV have evolved to… Expand
Minority HIV-1 Drug Resistance Mutations Are Present in Antiretroviral Treatment–Naïve Populations and Associate with Reduced Treatment Efficacy
Background Transmitted HIV-1 drug resistance can compromise initial antiretroviral therapy (ART); therefore, its detection is important for patient management. The absence of drug-associated… Expand
Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis.
- D. Kuhar, D. Henderson, +5 authors A. L. Panlilio
- Infection control and hospital epidemiology
- 5 August 2013
This report updates US Public Health Service recommendations for the management of healthcare personnel (HCP) who experience occupational exposure to blood and/or other body fluids that might contain… Expand
Multiple Groups of Novel Retroviral Genomes in Pigs and Related Species
ABSTRACT In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous… Expand
Prevalence of transmitted drug resistance associated mutations and HIV-1 subtypes in new HIV-1 diagnoses, U.S.–2006
Objective:To determine the distribution of HIV-1 subtypes and the prevalence of transmitted drug resistance-associated mutations (TDRM) among persons newly diagnosed with HIV-1 infection in the… Expand
The epidemiology of antiretroviral drug resistance among drug-naive HIV-1-infected persons in 10 US cities.
- H. Weinstock, Irum Zaidi, +13 authors J. Kaplan
- The Journal of infectious diseases
- 15 June 2004
BACKGROUND The prevalence and characteristics of persons with newly diagnosed human immunodeficiency virus (HIV) infections with or without evidence of mutations associated with drug resistance have… Expand