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Indinavir

Known as: (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-Pentonamide, Indinavir [Chemical/Ingredient], IDV 
A synthetic hydroxyaminopentane amide agent that selectively inhibits the protease of both human immunodeficiency virus 1 and 2. The incorporation of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
St John's wort reduced the area under the curve of the HIV-1 protease inhibitor indinavir by a mean of 57% (SD 19) and decreased… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Efavirenz is a nonnucleoside reverse-transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). We… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND After the addition of the protease inhibitor indinavir to combination drug regimens for HIV-1 infection, some patients… Expand
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Highly Cited
1998
Highly Cited
1998
Objective:To describe a syndrome of peripheral lipodystrophy (fat wasting of the face, limbs and upper trunk), hyperlipidaemia… Expand
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Highly Cited
1998
Highly Cited
1998
Currently available HIV-1 protease inhibitors are potent agents in the therapy of HIV-1 infection. However, limited oral… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The new protease inhibitors are potent inhibitors of the human immunodeficiency virus (HIV), and in combination with… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The efficacy and safety of adding a protease inhibitor to two nucleoside analogues to treat human immunodeficiency… Expand
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Highly Cited
1997
Highly Cited
1997
AIMS To compare the inhibitory potential of the HIV protease inhibitors saquinavir, ritonavir and indinavir against CYP1A2… Expand
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Review
1997
Review
1997
  • J. Lin, A. Lu
  • Pharmacological reviews
  • 1997
  • Corpus ID: 8187261
Drug research encompasses several diverse disciplines united by a common goal, namely the development of novel therapeutic agents… Expand
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Highly Cited
1996
Highly Cited
1996
Indinavir (IDV) (also called CRIXIVAN, MK-639, or L-735,524) is a potent and selective inhibitor of the human immunodeficiency… Expand
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