Skip to search formSkip to main contentSkip to account menu

Indinavir

Known as: (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-Pentonamide, Indinavir [Chemical/Ingredient], IDV 
A synthetic hydroxyaminopentane amide agent that selectively inhibits the protease of both human immunodeficiency virus 1 and 2. The incorporation of… 
National Institutes of Health

Related topics

Related topics

31 relations
Acquired Immunodeficiency SyndromeAstemizoleCYP3A7 protein, humanCisapride

Broader (3)

Antiviral AgentsHIV Protease InhibitorsProtease Inhibitors

Narrower (4)

CrixivanIndinavir SulfateL-735 524MK-639

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease
Highly Cited
2008
Highly Cited
2008
Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK.
Highly Cited
2006
Highly Cited
2006
Sensory neuropathy in human immunodeficiency virus/acquired immunodeficiency syndrome patients: Protease inhibitor–mediated neurotoxicity
Human immunodeficiency virus–associated sensory neuropathy (HIV‐SN) is a common and disabling disorder, often associated with… 
Highly Cited
2000
Highly Cited
2000
HIV protease inhibitors block adipogenesis and increase lipolysis in vitro.
Highly Cited
2000
Highly Cited
2000
Determination of twelve antiretroviral agents in human plasma sample using reversed-phase high-performance liquid chromatography.
Highly Cited
1999
Highly Cited
1999
Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery.
Highly Cited
1999
Highly Cited
1999
Indinavir Concentrations and Antiviral Effect
Study Objectives. To determine the variability of indinavir pharmacokinetics in patients attending an outpatient clinic, and to… 
Highly Cited
1997
Highly Cited
1997
Cytomegalovirus retinitis after initiation of highly active antiretroviral therapy
Highly Cited
1996
Highly Cited
1996
Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor
Indinavir (IDV) (also called CRIXIVAN, MK-639, or L-735,524) is a potent and selective inhibitor of the human immunodeficiency… 
Highly Cited
1996
Highly Cited
1996
Assessment of coronary arterial flow and flow reserve in humans with magnetic resonance imaging.
BACKGROUND The noninvasive measurement of absolute epicardial coronary arterial flow and flow reserve would be useful in the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)