Indinavir

Known as: (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-Pentonamide, Indinavir [Chemical/Ingredient], IDV 
A synthetic hydroxyaminopentane amide agent that selectively inhibits the protease of both human immunodeficiency virus 1 and 2. The incorporation of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
OBJECTIVES To determine the relative sensitivities of glucose transporter isoforms to the protease inhibitor indinavir and to… (More)
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Highly Cited
2001
Highly Cited
2001
Indinavir is a viral protease inhibitor used for the treatment of HIV infection. Unconjugated hyperbilirubinemia develops in up… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Therapy with HIV protease inhibitors (PI) has been associated with hyperglycemia, hyperlipidemia and changes in body… (More)
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Highly Cited
2001
Highly Cited
2001
CONTEXT Abacavir, a nucleoside analogue, has demonstrated suppression of human immunodeficiency virus (HIV) replication alone and… (More)
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Highly Cited
2000
Highly Cited
2000
St John's wort reduced the area under the curve of the HIV-1 protease inhibitor indinavir by a mean of 57% (SD 19) and decreased… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Efavirenz is a nonnucleoside reverse-transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). We… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND After the addition of the protease inhibitor indinavir to combination drug regimens for HIV-1 infection, some patients… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To describe a syndrome of peripheral lipodystrophy (fat wasting of the face, limbs and upper trunk), hyperlipidaemia… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The efficacy and safety of adding a protease inhibitor to two nucleoside analogues to treat human immunodeficiency… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The new protease inhibitors are potent inhibitors of the human immunodeficiency virus (HIV), and in combination with… (More)
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