Crixivan
National Institutes of Health
Papers overview
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The pharmaceutically important tetrahydro-[1,2,3]triazolopyrazine heterocyclic architecture has been synthesized via a concise…
Patients with schizophrenia are at significantly increased risk for infection with human immunodeficiency virus (HIV), hepatitis…
Two studies, concerning the synthesis of original nucleoside analogs regarded as an application of heterochemistry on…
Recent results from human clinical trials have established the critical role of HIV protease inhibitors in the treatment of…
Indene is oxidized to mixtures of cis- and trans-indandiols and related metabolites by Pseudomonas putida and Rhodococcus sp…
The new phase of North-South research collaboration was caught in a snapshot published recently in a popular weekly newsmagazine…
History tells us that when given a reasonably active lead compound, medicinal chemists usually are able to increase the potency…
Indinavir (IDV) (also called CRIXIVAN, MK-639, or L-735,524) is a potent and selective inhibitor of the human immunodeficiency…
: The Food and Drug Administration (FDA) approved two new protease inhibitors for treatment of AIDS. Ritonavir (Norvir) and…