Crixivan

Patients with schizophrenia are at significantly increased risk for infection with human immunodeficiency virus (HIV), hepatitis… Expand

Recent results from human clinical trials have established the critical role of HIV protease inhibitors in the treatment of… Expand

Indene is oxidized to mixtures of cis- and trans-indandiols and related metabolites by Pseudomonas putida and Rhodococcus sp… Expand

The new phase of North-South research collaboration was caught in a snapshot published recently in a popular weekly newsmagazine… Expand

A French study confirms recent reports of hair loss in men as a side effect of the protease inhibitor Crixivan (Indinavir). All… Expand

History tells us that when given a reasonably active lead compound, medicinal chemists usually are able to increase the potency… Expand

Indinavir (IDV) (also called CRIXIVAN, MK-639, or L-735,524) is a potent and selective inhibitor of the human immunodeficiency… Expand

In 1995 and 1996, the Food and Drug Administration (FDA) approved three products in the new protease inhibitor class of drugs… Expand

The Food and Drug Administration (FDA) approved two new protease inhibitors for treatment of AIDS. Ritonavir (Norvir) and… Expand

Merck's protease inhibitor, indinavir, has received Food and Drug Administration (FDA) approval, and is being made available… Expand