L-735 524

Known as: L 735 524, L 735,524, L735 524 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2007
02419942007

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Indinavir (IDV) (also called CRIXIVAN, MK-639, or L-735,524) is a potent and selective inhibitor of the human immunodeficiency… (More)
Is this relevant?
1996
1996
MK-639 (L-735,524) is a potent human immunodeficiency virus protease inhibitor under investigation in the treatment of acquired… (More)
Is this relevant?
1996
1996
Mutations in the human immunodeficiency virus (HIV) protease (L90M, G48V, and L90M/G48V) arise when HIV is passaged in the… (More)
Is this relevant?
1995
1995
Human immunodeficiency virus type 1 (HIV-1) protease inhibitor-resistant variants, isolated on passage of HIV-1HXB2 in MT-4 cells… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Eleven different recombinant, drug-resistant HIV-1 protease (HIV PR) mutants--R8Q, V32I, M46I, V82A, V82F, V82I, I84V, V32I/I84V… (More)
Is this relevant?
1995
1995
We have observed a high correlation between the intermolecular interaction energy (Einter) calculated for HIV-1 protease… (More)
Is this relevant?
1995
1995
L-735,524, N-[2(R)-hydroxy-1(S)-indanyl]-5-(2(S)-(1,1- dimethylethylaminocarbonyl)-4-[(pyridin-3-yl)methyl]piperazin++ +-1-yl)-4… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
To date, numerous inhibitors of the human immunodeficiency virus type 1 protease have been reported, but few have been studied… (More)
Is this relevant?
1994
1994
L-735,524 is a potent, orally bioavailable inhibitor of human immunodeficiency virus (HIV) protease currently in a Phase II… (More)
Is this relevant?
1994
1994
A series of HIV protease inhibitors possessing a hydroxylaminepentanamide transition state isostere have been developed… (More)
Is this relevant?