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IGF2R protein, human

Known as: Receptors, Insulin Like Growth Factor II, M6P/IGF2R, Receptors, IGF-2 
A receptor that is specific for IGF-II and mannose-6-phosphate. The receptor is a 250-kDa single chain polypeptide which is unrelated in structure to… 
National Institutes of Health

Related topics

Related topics

20 relations
Cell Proliferation Regulatory ProcessGrowth Factor Receptor GenesIGF2R geneIGF2R wt Allele

Papers overview

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Highly Cited
2009
Highly Cited
2009
Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size.
Myostatin is a negative regulator of skeletal muscle size, previously shown to inhibit muscle cell differentiation. Myostatin… 
Highly Cited
2006
Highly Cited
2006
Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease.
The cascade of Alzheimer's disease (AD) neurodegeneration is associated with persistent oxidative stress, mitochondrial… 
Highly Cited
2003
Highly Cited
2003
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.
Highly Cited
2000
Highly Cited
2000
Phosphorylation of the AMPA Receptor Subunit GluR2 Differentially Regulates Its Interaction with PDZ Domain-Containing Proteins
PSD-95, DLG, ZO-1 (PDZ) domain-mediated protein interactions have been shown to play important roles in the regulation of… 
Highly Cited
1998
Highly Cited
1998
Altered imprinted gene methylation and expression in completely ES cell-derived mouse fetuses: association with aberrant phenotypes.
In vitro manipulation of preimplantation mammalian embryos can influence differentiation and growth at later stages of… 
Highly Cited
1997
Highly Cited
1997
Imprinted expression of the Igf2r gene depends on an intronic CpG island
Gametic imprinting is a developmental process that induces parental-specific expression or repression of autosomal and X… 
Highly Cited
1993
Highly Cited
1993
Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.
The nuclear hormone receptors called PPARs (peroxisome proliferator-activated receptors alpha, beta, and gamma) regulate the… 
Highly Cited
1992
Highly Cited
1992
Potentiation of NMDA receptor currents by arachidonic acid
ARACHIDONIC acid is released by phospholipase A2 when activation of N-methyl-D-aspartate (NMDA) receptors by neurotransmitter… 
Highly Cited
1991
Highly Cited
1991
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus
T-ASSOCIATED maternal effect (Tme) is the only known maternal-effect mutation in the mouse1,2. The defect is nuclear-encoded3 and… 
Highly Cited
1989
Highly Cited
1989
EGF induces tyrosine phosphorylation of phospholipase C-II: A potential mechanism for EGF receptor signaling
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