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Glutamate Decarboxylase

Known as: Acid Decarboxylase, Glutamic, Decarboxylase, Glutamate, Glutamate Carboxy Lyase 
A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The… Expand
National Institutes of Health

Papers overview

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Review
2011
Review
2011
BACKGROUND Latent autoimmune diabetes in adults (LADA) is a slowly developing type 1 diabetes. OBJECTIVES To compare… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Dopaminergic neuronal loss in Parkinson's disease leads to changes in the circuitry of the basal ganglia, such as… Expand
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Highly Cited
2003
Highly Cited
2003
γ‐aminobutyric acid (GABA)ergic neurons in the central nervous system regulate the activity of other neurons and play a crucial… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Reelin (RELN) is a glycoprotein secreted preferentially by cortical gamma-aminobutyric acid-ergic (GABAergic… Expand
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Highly Cited
1997
Highly Cited
1997
Type 1, or insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease associated with loss of tolerance to several… Expand
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Highly Cited
1994
Highly Cited
1994
We have done a study designed to ascertain the effectiveness of measuring antibodies to glutamic acid decarboxylase (anti-GAD) in… Expand
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Highly Cited
1993
Highly Cited
1993
INSULIN-DEPENDENT diabetes mellitus (IDDM) in non-obese diabetic (NOD) mice results from the T-lymphocyte-mediated destruction of… Expand
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Highly Cited
1993
Highly Cited
1993
KNOWING the autoantigen target(s) in an organ-specific autoimmune disease is essential to understanding its pathogenesis. Insulin… Expand
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Highly Cited
1991
Highly Cited
1991
gamma-Aminobutyric acid (GABA) is the most widely distributed known inhibitory neurotransmitter in the vertebrate brain. GABA… Expand
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Highly Cited
1991
Highly Cited
1991
Glutamate decarboxylase (GAD) catalyzes the production of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter… Expand
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