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Glutamate Decarboxylase

Known as: Acid Decarboxylase, Glutamic, Decarboxylase, Glutamate, Glutamate Carboxy Lyase 
A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The… Expand
National Institutes of Health

Papers overview

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Review
2011
Review
2011
BACKGROUND Latent autoimmune diabetes in adults (LADA) is a slowly developing type 1 diabetes. OBJECTIVES To compare… Expand
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Highly Cited
2003
Highly Cited
2003
γ‐aminobutyric acid (GABA)ergic neurons in the central nervous system regulate the activity of other neurons and play a crucial… Expand
Highly Cited
2000
Highly Cited
2000
BACKGROUND Reelin (RELN) is a glycoprotein secreted preferentially by cortical gamma-aminobutyric acid-ergic (GABAergic… Expand
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Review
1998
Review
1998
Adults express two isoforms of glutamate decarboxylase (GAD), GAD67 and GAD65, which are encoded by different independently… Expand
Highly Cited
1994
Highly Cited
1994
We have done a study designed to ascertain the effectiveness of measuring antibodies to glutamic acid decarboxylase (anti-GAD) in… Expand
Highly Cited
1993
Highly Cited
1993
INSULIN-DEPENDENT diabetes mellitus (IDDM) in non-obese diabetic (NOD) mice results from the T-lymphocyte-mediated destruction of… Expand
Highly Cited
1993
Highly Cited
1993
KNOWING the autoantigen target(s) in an organ-specific autoimmune disease is essential to understanding its pathogenesis. Insulin… Expand
Highly Cited
1991
Highly Cited
1991
gamma-Aminobutyric acid (GABA) is the most widely distributed known inhibitory neurotransmitter in the vertebrate brain. GABA… Expand
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Highly Cited
1991
Highly Cited
1991
Abstract: Glutamate decarboxylase (GAD) catalyzes the production of γ‐aminobutyric acid (GABA), a major inhibitory… Expand
Highly Cited
1983
Highly Cited
1983
Immunocytochemical methods for peptides and serotonin have greatly advanced the study of neurones in which these substances are… Expand