Glutamate Decarboxylase

Known as: Acid Decarboxylase, Glutamic, Decarboxylase, Glutamate, Glutamate Carboxy Lyase 
A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1949-2018
010020019492017

Papers overview

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Highly Cited
2003
Highly Cited
2003
Gamma-aminobutyric acid (GABA)ergic neurons in the central nervous system regulate the activity of other neurons and play a… (More)
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Highly Cited
1996
Highly Cited
1996
We previously demonstrated that a spontaneous Th1 response against glutamate decarboxylase (GAD65) arises in NOD mice at four… (More)
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Highly Cited
1996
Highly Cited
1996
Glutamate decarboxylase (GAD) catalyzes the decarboxylation of glutamate to CO2 and gamma-aminobutyrate (GABA). GAD is ubiquitous… (More)
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Highly Cited
1994
Highly Cited
1994
Insulin-dependent diabetes (IDD) results from the autoimmune destruction of the insulin-producing pancreatic beta cells… (More)
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Highly Cited
1993
Highly Cited
1993
INSULIN-DEPENDENT diabetes mellitus (IDDM) in non-obese diabetic (NOD) mice results from the T-lymphocyte-mediated destruction of… (More)
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Highly Cited
1992
Highly Cited
1992
Insulin-dependent diabetes mellitus (IDDM) is thought to result from the autoimmune destruction of the insulin-producing beta… (More)
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Highly Cited
1991
Highly Cited
1991
gamma-Aminobutyric acid (GABA) is the most widely distributed known inhibitory neurotransmitter in the vertebrate brain. GABA… (More)
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Highly Cited
1991
Highly Cited
1991
Glutamate decarboxylase (GAD) catalyzes the production of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter… (More)
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Highly Cited
1989
Highly Cited
1989
The present study was designed to determine whether inhibitory neurons in human epileptic hippocampus are reduced in number… (More)
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Highly Cited
1983
Highly Cited
1983
Immunocytochemical methods for peptides and serotonin have greatly advanced the study of neurones in which these substances are… (More)
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