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GAD1 gene
Known as:
GLUTAMATE DECARBOXYLASE 1
, GAD
, GAD1
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National Institutes of Health
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Related topics
Related topics
4 relations
GAD2 gene
Glutamate Decarboxylase
Glutamic Acid Decarboxylase 1 Measurement
glutamate decarboxylase 1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane‐exposed adults
K. Koenen
,
A. Amstadter
,
+4 authors
J. Gelernter
Depression and Anxiety
2009
Corpus ID: 22618337
Background: Generalized anxiety disorder (GAD) is a common and sometimes disabling condition often associated with stressful life…
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Highly Cited
2007
Highly Cited
2007
Role of glutamate decarboxylase (GAD) isoform, GAD65, in GABA synthesis and transport into synaptic vesicles—Evidence from GAD65-knockout mice studies
Heng Wu
,
Ying Jin
,
+7 authors
Jang-Yen Wu
Brain Research
2007
Corpus ID: 41459108
Highly Cited
2003
Highly Cited
2003
Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells.
James E. Greening
,
T. Tree
,
+4 authors
M. Peakman
Diabetes
2003
Corpus ID: 6704150
Type 1 diabetes is characterized by T-cell infiltration of the islets of Langerhans and abundant HLA class II molecule expression…
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Highly Cited
2002
Highly Cited
2002
Islet autoantibodies, nationality and gender: a multinational screening study in first-degree relatives of patients with Type I diabetes
A. Williams
,
P. Bingley
,
W. P. Moore
,
E. Gale
,
A. T. N. Group
Diabetologia
2002
Corpus ID: 2705618
Aims/hypothesisFirst-degree relatives of patients with Type I (insulin-dependent) diabetes mellitus diagnosed at 20 years of age…
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Review
1999
Review
1999
GABA and epileptogenesis: comparing gabrb3 gene-deficient mice with Angelman syndrome in man
T. Delorey
,
R. Olsen
Epilepsy Research
1999
Corpus ID: 13656488
Highly Cited
1995
Highly Cited
1995
Targeting of the 67-kDa Isoform of Glutamic Acid Decarboxylase to Intracellular Organelles Is Mediated by Its Interaction with the NH2-terminal Region of the 65-kDa Isoform of Glutamic Acid…
R. Dirkx
,
Annette Thomas
,
+4 authors
M. Solimena
Journal of Biological Chemistry
1995
Corpus ID: 25342260
The two isoforms of glutamic acid decarboxylase (GAD), GAD67 and GAD65, synthesize the neurotransmitter γ-aminobutyric acid in…
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Highly Cited
1993
Highly Cited
1993
Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin- dependent diabetes
Margo C. Honeyman
,
David S. Cram
,
Leonard C. Harrison
Journal of Experimental Medicine
1993
Corpus ID: 22198816
Glutamic acid decarboxylase (GAD) has been shown to be a target of autoantibodies in insulin-dependent diabetes (IDD). Two forms…
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Highly Cited
1993
Highly Cited
1993
Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat.
B. Faulkner-Jones
,
D. Cram
,
J. Kun
,
L. Harrison
Endocrinology
1993
Corpus ID: 34745248
Glutamic acid decarboxylase (GAD) catalyzes synthesis of the inhibitory neurotransmitter gamma-amino butyric acid. Two homologous…
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Highly Cited
1986
Highly Cited
1986
In situ hybridization to localize mRNA encoding the neurotransmitter synthetic enzyme glutamate decarboxylase in mouse cerebellum.
C. Wuenschell
,
R. Fisher
,
D. Kaufman
,
A. Tobin
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 23183083
Glutamate decarboxylase (GAD; EC 4.1.1.15) is responsible for the synthesis of the neurotransmitter gamma-aminobutyric acid (GABA…
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Highly Cited
1974
Highly Cited
1974
Choline acetyltransferase and acetylcholinesterase in fascia dentata following lesion of the entorhinal afferents.
J. Storm-Mathisen
Brain Research
1974
Corpus ID: 24111620
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