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glutamate decarboxylase 1

Known as: GAD1 enzyme, GAD67 enzyme, glutamate decarboxylase GAD67 
 
National Institutes of Health

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GAD1 gene

Broader (1)

Glutamate Decarboxylase

Papers overview

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2016
2016
The NMDA receptor GluN2C subunit controls cortical excitatory-inhibitory balance, neuronal oscillations and cognitive function
Despite strong evidence for NMDA receptor (NMDAR) hypofunction as an underlying factor for cognitive disorders, the precise roles… Expand
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2015
2015
Differential distribution of GABA and glycine terminals in the inferior colliculus of rat and mouse.
The inferior colliculus (IC), the midbrain component of the auditory pathway, integrates virtually all inputs from the auditory… Expand
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2011
2011
The Notch effector gene Hes1 regulates migration of hypothalamic neurons, neuropeptide content and axon targeting to the pituitary.
Proper development of the hypothalamic-pituitary axis requires precise neuronal signaling to establish a network that regulates… Expand
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2010
2010
Alteration of inhibitory circuits in the somatosensory cortex of Ts65Dn mice, a model for Down’s syndrome
Down’s syndrome (DS), with an incidence of one in 800 live births, is the most common genetic disorder associated with mental… Expand
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Highly Cited
2007
Highly Cited
2007
Prefrontal Dysfunction in Schizophrenia Involves Mixed-Lineage Leukemia 1-Regulated Histone Methylation at GABAergic Gene Promoters
Alterations in GABAergic mRNA expression play a key role for prefrontal dysfunction in schizophrenia and other neurodevelopmental… Expand
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2006
2006
Kappa opioid receptor (KOR) and GAD67 immunoreactivity are found in OFF and NEUTRAL cells in the rostral ventromedial medulla.
This study combines functional and anatomical characterization of neurons in the rostral ventromedial medulla (RVM) to show… Expand
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Highly Cited
2003
Highly Cited
2003
Distribution and colocalisation of glutamate decarboxylase isoforms in the rat spinal cord
The inhibitory neurotransmitter GABA is synthesized by glutamic acid decarboxylase (GAD), and two isoforms of this enzyme exist… Expand
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1998
1998
Mutation and polymorphic marker analyses of 65K- and 67K-glutamate decarboxylase genes in two families with pyridoxine-dependent epilepsy
AbstractPyridoxine-dependent epilepsy is a disease inherited as an autosomal recessive trait, characterized by rapid response to… Expand
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1994
1994
Differential localization of two glutamic acid decarboxylases (GAD65 and GAD67) in adult monkey visual cortex.
Adult monkey primary visual cortex contains a diverse population of stellate neurons that utilize the neurotransmitter gamma… Expand
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1993
1993
Expression of GAD (Mr 67,000) and Its Messenger RNA in Basal Ganglia and Cerebral Cortex after Ischemic Cortical Lesions in Rats
Glutamic acid decarboxylase (GAD) is present in most efferent neurons of the striatum and in interneurons both in the striatum… Expand
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