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GRM8 gene

Known as: GRM8, GPRC1H, glutamate metabotropic receptor 8 
This gene plays a role in G protein-coupled receptor signaling.
National Institutes of Health

Related topics

Related topics

8 relations
G Protein-Coupled Receptor SignalingLigand BindingMetabotropic Glutamate Receptor 8, humanReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
A Deep Learning Approach for Predicting Antidepressant Response in Major Depression Using Clinical and Genetic Biomarkers
In the wake of recent advances in scientific research, personalized medicine using deep learning techniques represents a new… 
Highly Cited
2012
Highly Cited
2012
Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer
Endometrial cancer is the most common gynecological malignancy, with more than 280,000 cases occurring annually worldwide… 
Review
2010
Review
2010
Diverse somatic mutation patterns and pathway alterations in human cancers.
The systematic characterization of somatic mutations in cancer genomes is essential for understanding the disease and for… 
Highly Cited
2010
Highly Cited
2010
Genome-Wide Association Scan of Trait Depression
Highly Cited
2009
Highly Cited
2009
Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event‐related oscillations and alcohol dependence
Evidence suggests the P3 amplitude of the event‐related potential and its underlying superimposed event‐related oscillations… 
Highly Cited
2004
Highly Cited
2004
Positive associations of polymorphisms in the metabotropic glutamate receptor type 8 gene (GRM8) with schizophrenia
The glutamatergic dysfunction has been implicated in pathophysiology of schizophrenia. The Group III metabotropic glutamate… 
Highly Cited
2002
Highly Cited
2002
Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists
Ca2+, pheromones, sweet taste compounds, and the main neurotransmitters glutamate and γ-aminobutyric acid activate G protein… 
2002
2002
Modulation of lateral perforant path excitatory responses by metabotropic glutamate 8 (mGlu8) receptors
1997
1997
The human metabotropic glutamate receptor 8 (GRM8) gene: a disproportionately large gene located at 7q31.3-q32.1.
Metabotropic glutamate receptors (GRMs), which constitute a family of genes, are neurotransmitter receptors that respond to… 
1996
1996
Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.
Metabotropic glutamate receptors (GRMs) are neurotransmitter receptors that respond to glutamate stimulations by activating GTP… 
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