Receptor Signaling

Innate immune signals mediated by Toll-like receptors (TLRs) have been thought to contribute considerably to the antibody… Expand

Toll-like receptor (TLR) signals that initiate innate immune responses to pathogens must be tightly regulated to prevent… Expand

Cytokines of the interleukin-1 (IL-1) family, such as IL-1 alpha/beta and IL-18, have important functions in host defense, immune… Expand

The cannabinoid receptor family currently includes two types: CB1, characterized in neuronal cells and brain, and CB2… Expand

The insulin receptor (IR) is expressed in various regions of the developing and adult brain, and its functions have become the… Expand

Toll-like receptor (TLR) activation is central to immunity, wherein the activation of the TLR9 subfamily members TLR9 and TLR7… Expand

The Toll-like receptor–interleukin 1 receptor signaling (TLR–IL-1R) receptor superfamily is important in differentially… Expand

Heat shock proteins (HSPs) require no adjuvant to confer immunogenicity to bound peptides, as if they possessed an intrinsic… Expand

Epidermal growth factor receptor (EGFR) signaling was analyzed in mammalian cells conditionally defective for receptor-mediated… Expand

Like other cell-surface receptors with intrinsic or associated protein-tyrosine kinase activity, the T-cell receptor complex… Expand