Receptor Signaling

An intercellular process that involves a cellular receptor binding to a cognate ligand and results in a specific cellular response.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Cryopyrin is essential for caspase-1 activation triggered by Toll-like receptor (TLR) ligands in the presence of adenosine… (More)
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Highly Cited
2006
Highly Cited
2006
Innate immune signals mediated by Toll-like receptors (TLRs) have been thought to contribute considerably to the antibody… (More)
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Highly Cited
2005
Highly Cited
2005
Cytokines of the interleukin-1 (IL-1) family, such as IL-1 alpha/beta and IL-18, have important functions in host defense, immune… (More)
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Review
2004
Review
2004
While the hormone leptin and its receptor were discovered relatively recently, a great deal is already known about the molecular… (More)
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Highly Cited
2003
Highly Cited
2003
We previously reported a new Toll/IL-1R (TIR)-containing molecule, named TIR domain-containing adaptor inducing IFN-beta (TRIF… (More)
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Highly Cited
2003
Highly Cited
2003
The Toll-like receptor–interleukin 1 receptor signaling (TLR–IL-1R) receptor superfamily is important in differentially… (More)
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Highly Cited
2002
Highly Cited
2002
MyD88 is a Toll/IL-1 receptor (TIR) domain-containing adapter common to signaling pathways via Toll-like receptor (TLR) family… (More)
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Highly Cited
2001
Highly Cited
2001
Heat shock proteins (HSPs) require no adjuvant to confer immunogenicity to bound peptides, as if they possessed an intrinsic… (More)
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Highly Cited
1996
Highly Cited
1996
Epidermal growth factor receptor (EGFR) signaling was analyzed in mammalian cells conditionally defective for receptor-mediated… (More)
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Highly Cited
1995
Highly Cited
1995
  • T. Mckeithan
  • Proceedings of the National Academy of Sciences…
  • 1995
Like other cell-surface receptors with intrinsic or associated protein-tyrosine kinase activity, the T-cell receptor complex… (More)
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