EZH2 wt Allele

Known as: ENX-1, Enhancer of Zeste Homolog 2 (Drosophila) wt Allele, MGC9169 
Human EZH2 wild-type allele is located within 7q35-q36 and is approximately 77 kb in length. This allele, which encodes enhancer of zeste homolog 2… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
051019962018

Papers overview

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2015
2015
Polycomb repressive complex 2 (PRC2) plays crucial roles in transcriptional regulation and stem cell development. However, the… (More)
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2015
2015
Enhancer of zeste homolog 2 (EZH2) and related EZH1 control gene expression and promote tumorigenesis via methylating histone H3… (More)
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Highly Cited
2013
Highly Cited
2013
EZH2 or EZH1 is the catalytic subunit of the polycomb repressive complex 2 that catalyzes methylation of histone H3 lysine 27… (More)
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Highly Cited
2013
Highly Cited
2013
Polycomb group (PcG) proteins are essential regulators of hematopoietic stem cells. Recent extensive mutation analyses of the… (More)
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2013
2013
The histone methyltransferase enhancer of Zeste homolog 2 (EZH2) is a candidate oncogene due to its prevalent overexpression in… (More)
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2013
2013
Epithelial-mesenchymal transition (EMT) is known to impart metastasis and stemness characteristics in breast cancer. To… (More)
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2013
2013
Polycomb-repressive complex 2 (PRC2) comprises specific members of the Polycomb group of epigenetic modulators. PRC2 catalyzes… (More)
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Highly Cited
2011
Highly Cited
2011
Polycomb-group (PcG) proteins are essential regulators of hematopoietic stem cells (HSCs). In contrast to Bmi1, a component of… (More)
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Highly Cited
2008
Highly Cited
2008
Trimethylation on H3K27 (H3K27me3) mediated by Polycomb repressive complex 2 (PRC2) has been linked to embryonic stem cell (ESC… (More)
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Highly Cited
2008
Highly Cited
2008
Polycomb group proteins are critical to maintaining gene repression established during Drosophila development. Part of this group… (More)
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