EZH2 protein, human

Known as: ENX-1 protein, human, Histone-Lysine N-Methyltransferase EZH2, ENX-1 
Histone-lysine N-methyltransferase EZH2 (746 aa, ~85 kDa) is encoded by the human EZH2 gene. This protein is involved in the regulation of chromatin… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
In eukaryotes, post-translational modification of histones is critical for regulation of chromatin structure and gene expression… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Abnormalities of chromosome 7q are common in myeloid malignancies, but no specific target genes have yet been identified. Here… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase that contributes to the epigenetic silencing of… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Enhancer of zeste homolog 2 (EZH2) is a critical component of the polycomb-repressive complex 2 (PRC2), which is involved in gene… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
SUZ12 is a recently identified Polycomb group (PcG) protein, which together with EZH2 and EED forms different Polycomb repressive… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The Ezh2 protein endows the Polycomb PRC2 and PRC3 complexes with histone lysine methyltransferase (HKMT) activity that is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The Polycomb Group Protein EZH2 is a transcriptional repressor involved in controlling cellular memory and has been linked to… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Recent experiments have demonstrated that the Polycomb group (PcG) gene EZH2 is highly expressed in metastatic prostate cancer… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Prostate cancer is a leading cause of cancer-related death in males and is second only to lung cancer. Although effective… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Polycomb-group (Pc-G) genes are required for the stable repression of the homeotic selector genes and other developmentally… (More)
Is this relevant?