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EZH2 gene

Known as: ENX1, KMT6, ENHANCER OF ZESTE, DROSOPHILA, HOMOLOG 2 
This gene plays a role in chromatin remodeling and transcriptional regulation.
National Institutes of Health

Related topics

Related topics

6 relations
EZH2 protein, humanMetastatic Prostate CarcinomaTranscriptional Repressionchromatin remodeling

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EZH2 wt Allele

Papers overview

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2017
2017
Altered EZH2 splicing and expression is associated with impaired histone H3 lysine 27 tri-Methylation in myelodysplastic syndrome.
Highly Cited
2014
Highly Cited
2014
Ezh2 Regulates Transcriptional and Posttranslational Expression of T-bet and Promotes Th1 Cell Responses Mediating Aplastic Anemia in Mice
Acquired aplastic anemia (AA) is a potentially fatal bone marrow (BM) failure syndrome. IFN-γ–producing Th1 CD4+ T cells mediate… 
2014
2014
The Polycomb Protein Ezh2 Impacts on Induced Pluripotent Stem Cell Generation
Reprogramming of somatic cells toward pluripotency involves extensive chromatin reorganization and changes in gene expression… 
2013
2013
Effects of EZH2 Polymorphisms on Susceptibility to and Pathological Development of Hepatocellular Carcinoma
Background The enhancer of zeste 2 (EZH2) gene encodes the histone methyltransferase that is the catalytic component of the… 
Review
2013
Review
2013
From neural development to cognition: unexpected roles for chromatin
Nature Reviews Genetics 14, 347–359 (2013) In the above article, some of the references citations were incorrectly numbered in… 
2005
2005
Mutation screen and association study of EZH2 as a susceptibility gene for aggressive prostate cancer
Several linkage studies have provided evidence for a prostate cancer aggressiveness gene on chromosome 7q. This report details… 
2004
2004
Identification of polycomb group protein enhancer of zeste homolog 2 (EZH2)‐derived peptides immunogenic in HLA‐A24+ prostate cancer patients
Antigens overexpressed in metastatic prostate cancer are appropriate targets in anti‐cancer immunotherapy, and one candidate is… 
2000
2000
Proliferative involvement of ENX‐1, a putative human Polycomb group gene, in haematopoietic cells
Homeobox genes have important roles in haematopoiesis and are regulated in an activated state by the trithorax group (trxG) of… 
Highly Cited
1998
Highly Cited
1998
Interaction of Mouse Polycomb-Group (Pc-G) Proteins Enx1 and Enx2 with Eed: Indication for Separate Pc-G Complexes
ABSTRACT The Polycomb group (Pc-G) constitutes an important, functionally conserved group of proteins, required to stably… 
Highly Cited
1996
Highly Cited
1996
The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution.
The Drosophila Enhancer of zeste [E(z)] gene is a member of the Polycomb-group and, as such, is involved in maintaining the… 
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