EZH2 gene

Known as: ENX1, KMT6, ENHANCER OF ZESTE, DROSOPHILA, HOMOLOG 2 
This gene plays a role in chromatin remodeling and transcriptional regulation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Glioblastoma multiforme (GBM) displays cellular hierarchies harboring a subpopulation of stem-like cells (GSCs). Enhancer of… (More)
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Highly Cited
2011
Highly Cited
2011
Next-generation sequencing of follicular lymphoma and diffuse-large B-cell lymphoma has revealed frequent somatic, heterozygous… (More)
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Highly Cited
2010
Highly Cited
2010
Abnormalities of chromosome 7q are common in myeloid malignancies, but no specific target genes have yet been identified. Here… (More)
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Highly Cited
2010
Highly Cited
2010
In myelodysplastic syndromes (MDS), deletions of chromosome 7 or 7q are common and correlate with a poor prognosis. The relevant… (More)
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Highly Cited
2009
Highly Cited
2009
The Polycomb Repressive Complex 2 (PRC2) mediates epigenetic gene silencing by trimethylating histone H3 lysine 27 (H3K27me3) and… (More)
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Highly Cited
2008
Highly Cited
2008
Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase that contributes to the epigenetic silencing of… (More)
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Highly Cited
2008
Highly Cited
2008
Trimethylation on H3K27 (H3K27me3) mediated by Polycomb repressive complex 2 (PRC2) has been linked to embryonic stem cell (ESC… (More)
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Highly Cited
2008
Highly Cited
2008
Polycomb group proteins are critical to maintaining gene repression established during Drosophila development. Part of this group… (More)
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Highly Cited
2008
Highly Cited
2008
Enhancer of zeste homolog 2 (EZH2) is a critical component of the polycomb-repressive complex 2 (PRC2), which is involved in gene… (More)
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Highly Cited
2004
Highly Cited
2004
SUZ12 is a recently identified Polycomb group (PcG) protein, which together with EZH2 and EED forms different Polycomb repressive… (More)
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