Transcriptional Repression

Known as: Gene Down-Regulation, Gene Repression, Transcription Repression 
Decreased expression of some gene product.

Topic mentions per year

Topic mentions per year

1967-2018
0204019672018

Papers overview

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2015
2015
Histone H2A monoubiquitylation (H2Aub) is considered to be a key effector in transcriptional repression by Polycomb-repressive… (More)
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Highly Cited
2012
Highly Cited
2012
Transcription factors activate or repress target gene expression or switch between activation and repression. In animals and… (More)
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Highly Cited
2010
Highly Cited
2010
Recently, more than 1000 large intergenic noncoding RNAs (lincRNAs) have been reported. These RNAs are evolutionarily conserved… (More)
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Highly Cited
2008
Highly Cited
2008
DNA damage results in activation or suppression of transcription of a large number of genes. Transcriptional activation has been… (More)
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Highly Cited
2007
Highly Cited
2007
Histone methylation is crucial for regulating chromatin structure, gene transcription and the epigenetic state of the cell. LSD1… (More)
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Highly Cited
2005
Highly Cited
2005
Transcriptional dysregulation has emerged as a potentially important pathogenic mechanism in Huntington's disease, a… (More)
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Highly Cited
2003
Highly Cited
2003
With the discovery of RNA interference (RNAi) and related phenomena, new regulatory roles attributed to RNA continue to emerge… (More)
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Highly Cited
2002
Highly Cited
2002
Transcription factors and RNA polymerase II can be modified by O-linked N-acetylglucosamine (O-GlcNAc) monosaccharides at serine… (More)
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Highly Cited
2002
Highly Cited
2002
Covalent modifications of chromatin have emerged as key determinants of the genome's transcriptional competence. Histone H3… (More)
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Highly Cited
1997
Highly Cited
1997
Transcriptional repression by Mad-Max heterodimers requires interaction of Mad with the corepressors mSin3A/B. Sin3p, the S… (More)
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