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Gene Silencing Pathway

Known as: The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails 
Packaging of DNA into chromatin allows the cell to store its genetic information efficiently and has an important role in regulating gene expression… 
National Institutes of Health

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14 relations
BMI1 protein, humanCBX4 wt AlleleE3 SUMO-protein ligase CBX4EED wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Structure of precursor microRNA’s terminal loop regulates human Dicer’s dicing activity by switching DExH/D domain
Almost all pre-miRNAs in eukaryotic cytoplasm are recognized and processed into double-stranded microRNAs by the endonuclease… 
2011
2011
Meiotic crossover: what controls the breaks?
Meiotic crossover (CO) formation establishes the physical linkages between duplicated meiotic chromosomes. These COs are required… 
2009
2009
Transcriptional gene silencing using small RNAs.
RNA interference is a potent gene silencing pathway initiated by short molecules of double-stranded RNA. Small interfering RNAs… 
2009
2009
Identification of Cas6 as an endoribonuclease involved in CRISPR-mediated genome defense in prokaryotes
An RNA-based gene silencing pathway that protects bacteria and archaea from viruses and other genome invaders is hypothesized to… 
2008
2008
Recent Application of Intronic MicroRNA Agents in Cosmetics
Utilization of gene silencing effectors, such as microRNA (miRNA) and small hairpin RNA (shRNA), provides a powerful new strategy… 
2005
2005
Biochemical Mechanism of RNA Interference in Higher Organisms: A Dissertation
RNA interference (RNAi) is an evolutionarily conserved, sequence-specific gene silencing pathway found in eukaryotes, in which 21… 
Review
2004
Review
2004
The Long Processes of Short Interfering RNAs – RNA Interference and Its Implications in Neuronal Cells
Reverse genetics has been greatly advanced by the discovery of RNA interference (RNAi). This intracellular RNA-mediated gene… 
Review
2004
Review
2004
Exploring the genetic basis of disease using RNA interference
Cancer and autoimmunity are polygenic diseases. In order to better understand the mechanisms of disease development and… 
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