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A mechanism for initiating RNA-dependent RNA polymerization
In most RNA viruses, genome replication and transcription are catalysed by a viral RNA-dependent RNA polymerase. Double-stranded RNA viruses perform these operations in a capsid (the polymeraseExpand
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What does structure tell us about virus evolution?
Viruses are the most abundant life form and infect practically all organisms. Consequently, these obligate parasites are a major cause of human suffering and economic loss. The organization andExpand
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Insights into assembly from structural analysis of bacteriophage PRD1
The structure of the membrane-containing bacteriophage PRD1 has been determined by X-ray crystallography at about 4 Å resolution. Here we describe the structure and location of proteins P3, P16, P30Expand
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qiRNA is a new type of small interfering RNA induced by DNA damage
RNA interference pathways use small RNAs to mediate gene silencing in eukaryotes. In addition to small interfering RNAs (siRNAs) and microRNAs, several types of endogenously produced small RNAs haveExpand
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Structure unifies the viral universe.
Is it possible to meaningfully comprehend the diversity of the viral world? We propose that it is. This is based on the observation that, although there is immense genomic variation, every infectiveExpand
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Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2015)
Changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses in February 2015 are listed.
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Structure and host-cell interaction of SH1, a membrane-containing, halophilic euryarchaeal virus
The Archaea, and the viruses that infect them, are the least well understood of all of the three domains of life. They often grow in extreme conditions such as hypersaline lakes and sulfuric hotExpand
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Viral Evolution Revealed by Bacteriophage PRD1 and Human Adenovirus Coat Protein Structures
The unusual bacteriophage PRD1 features a membrane beneath its icosahedral protein coat. The crystal structure of the major coat protein, P3, at 1.85 A resolution reveals a molecule with threeExpand
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Do viruses form lineages across different domains of life?
  • D. Bamford
  • Biology, Medicine
  • Research in microbiology
  • 1 May 2003
The scarce characterisation of the viral world has hampered our efforts to appreciate the magnitude and diversity of the viral domain. It appears that almost every species can be infected by a numberExpand
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Global network of specific virus-host interactions in hypersaline environments.
Hypersaline environments are dominated by archaea and bacteria and are almost entirely devoid of eukaryotic organisms. In addition, hypersaline environments contain considerable numbers of viruses.Expand
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