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E3 SUMO-protein ligase CBX4

Known as: hPc2, Chromobox Protein Homolog 4, Pc2 
E3 SUMO-protein ligase CBX4 (558 aa, ~61 kDa) is encoded by the human CBX4 gene. This soluble, nuclear protein plays a role in repressing the… 
National Institutes of Health

Related topics

Related topics

10 relations
CBX4 geneCBX4 wt AlleleChromatin Remodeling FactorGene Silencing Pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Role of CBX4 in the Colorectal Carcinoma Metastasis-Response.
In our article ([1][1]), we have reported that CBX4 may serve as a tumor suppressor in colorectal carcinoma by recruiting HDAC3… 
2016
2016
Conformational dynamics of Ca2+-dependent responses in the polycystin-2 C-terminal tail.
PC2 (polycystin-2) forms a Ca(2+)-permeable channel in the cell membrane and its function is regulated by cytosolic Ca(2+) levels… 
2014
2014
The number and location of EF hand motifs dictates the calcium dependence of polycystin‐2 function
Polycystin 2 (PC2) is a calcium‐dependent calcium channel, and mutations to human PC2 (hPC2) are associated with polycystic… 
2012
2012
Phosphate disruption and metal toxicity in Saccharomyces cerevisiae: effects of RAD23 and the histone chaperone HPC2.
2008
2008
DNA methyltransferase 3B acts as a co-repressor of the human polycomb protein hPc2 to repress fibroblast growth factor receptor 3 transcription.
2005
2005
[Construction of eukaryotic expression vector for HPC2 and its expression in HEK293 cells].
OBJECTIVE To construct the eukaryotic expression vector for HPC2 for expression in HEK293 cells. METHODS HPC2 from pcDNA3/HPC2… 
2003
2003
The interactions of LIM protein KyoT with polycomb proteins.
  • Rong LiRu Zhang
  • Sheng wu hua xue yu sheng wu wu li xue bao Acta…
  • 2003
  • Corpus ID: 21026125
LIM domain protein KyoT interacts with transcription factor RBP-J and modulates Notch signaling pathway. To study the function of… 
Highly Cited
1997
Highly Cited
1997
Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis
Polycomb (Pc) is involved in the stable and heritable repression of homeotic gene activity during Drosophila development. Here… 
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