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BMI1 protein, human

Known as: Leukemia Viral BMI-1 Oncogene Homolog, RING Finger Protein 51, DNA Binding Protein BMI-1 
Polycomb complex protein BMI-1 (326 aa, ~37 kDa) is encoded by the human BMI1 gene. This protein is involved in transcriptional repression during… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The small intestine epithelium undergoes rapid and continuous regeneration supported by crypt intestinal stem cells (ISCs). Bmi1… Expand
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Highly Cited
2010
Highly Cited
2010
The epithelial–mesenchymal transition (EMT), one of the main mechanisms underlying development of cancer metastasis, induces stem… Expand
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Highly Cited
2009
Highly Cited
2009
Mice deficient in the Polycomb repressor Bmi1 develop numerous abnormalities including a severe defect in stem cell self-renewal… Expand
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Highly Cited
2009
Highly Cited
2009
Glioblastoma multiforme (GBM) is one of the most common and aggressive types of brain tumors. In GBM, a subpopulation of CD133… Expand
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Highly Cited
2008
Highly Cited
2008
Bmi1 plays an essential part in the self-renewal of hematopoietic and neural stem cells. To investigate its role in other adult… Expand
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Highly Cited
2007
Highly Cited
2007
The Polycomb group and oncogene Bmi1 is required for the proliferation of various differentiated cells and for the self-renewal… Expand
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Highly Cited
2006
Highly Cited
2006
Polycomb group proteins Ring1b and Bmi1 (B-cell-specific Moloney murine leukaemia virus integration site 1) are critical… Expand
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Review
2004
Review
2004
Stem cells generate the differentiated cell types within many organs throughout the lifespan of an organism and are thus… Expand
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Highly Cited
2004
Highly Cited
2004
Overexpression of the polycomb group gene Bmi1 promotes cell proliferation and induces leukaemia through repression of Cdkn2a… Expand
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Highly Cited
2004
Highly Cited
2004
Covalent modification of histones is important in regulating chromatin dynamics and transcription. One example of such… Expand
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