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BMI1 protein, human

Known as: Leukemia Viral BMI-1 Oncogene Homolog, RING Finger Protein 51, DNA Binding Protein BMI-1 
Polycomb complex protein BMI-1 (326 aa, ~37 kDa) is encoded by the human BMI1 gene. This protein is involved in transcriptional repression during… 
National Institutes of Health

Related topics

Related topics

13 relations
BMI1 geneBMI1 wt AlleleCYS2-HIS2 Zinc FingersCell Nucleus

Broader (1)

PRC1 Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Senescence Mediated by p16INK4a Impedes Reprogramming of Human Corneal Endothelial Cells into Neural Crest Progenitors
Human corneal endothelial cells (HCECs) have limited proliferative capacity due to “contact-inhibition” at G1 phase. Such contact… 
2015
2015
Correction: Corrigendum: Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence
Nature Communications 6: Article number: 6473 (2015); Published: 9 March 2015; Updated: 14 May 2015 In the original version of… 
2015
2015
Bmi 1 is required for the initiation of pancreatic cancer through an Ink 4 a-independent mechanism
Epigenetic dysregulation is involved in the initiation and progression of many epithelial cancers. BMI1, a component of the… 
2015
2015
Knockdown of Bmi1 inhibits bladder cancer cell growth both in vitro and in vivo by blocking cell cycle at G1 phase and inducing apoptosis
Bmi1 is a member of the polycomb group family of proteins, and it drives the carcinogenesis of various cancers and governs the… 
2013
2013
Elevated expression of Bmi1 in hepatocellular carcinoma with bile duct tumor thrombi.
BACKGROUND/AIMS Hepatocellular carcinoma (HCC) with bile duct tumor thrombi (BDTT) is a rare event. The Bmi1 gene has been… 
2012
2012
Abstract SY05-03: microRNAs, EMT, and cancer stem cells
We have shown, that in particular tumor cells at the invasive front undergo an epithelial-mesenchymal transition (EMT) and… 
2011
2011
Direct Activation of Bmi 1 by Twist 1 : Implications in Cancer Stemness , Epithelial-Mesenchymal Transition , and Clinical Significance
Cancer stemness is a concept used to describe a minor population of cells (cancer stem cells-CSCs) residing in a tumor, which… 
2011
2011
BMI 1 promotes the progression of laryngeal squamous cell carcinoma
BMI1 is highly expressed in several malignant tumors, and its expression level is associated with tumor progression… 
2011
2011
Relationship between Notch signal transduction pathway and expression of Bmi1 in colorectal caner cells
Objective To investigate the Notch1 and Bmi1 protein levels in human colorectal cancer samples and their correlation with… 
Highly Cited
2010
Highly Cited
2010
The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors
Polycomb group (PcG) proteins are overexpressed in several human malignancies including breast cancer. In particular, aberrant… 
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