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DX 619

Known as: DX-619, DX619 compound 
 
National Institutes of Health

Papers overview

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2012
2012
PurposeTo examine the effect of the fluoroquinolone DX-619 on CYP3A4 and urinary excretion of 6β-hydroxycortisol, an endogenous… Expand
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Highly Cited
2011
Highly Cited
2011
The aim of this study was to examine the mechanism underlying the elevation in serum creatinine levels caused by a novel des… Expand
2010
2010
Quinolone antibacterial agents are extensively utilized in antimicrobial chemotherapy. However, they have been reported to induce… Expand
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2006
2006
ABSTRACT Highly virulent, community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains with Panton-Valentine… Expand
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2006
2006
Interactions of DX-619, a novel fluoroquinolone antibacterial, and levofloxacin (LVFX) with the human renal organic cation… Expand
2006
2006
ABSTRACT The in vitro activity of DX-619, a new des-F(6) quinolone, against anaerobic bacteria was evaluated. DX-619 showed… Expand
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2005
2005
ABSTRACT The in vitro activities of DX-619, des-fluoro(6) quinolone, against 1,208 clinical isolates were examined. DX-619 was… Expand
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2005
2005
ABSTRACT DX-619, a novel des-fluoro(6) quinolone, was 16- to 32-fold, twofold, and four- to eightfold more potent than… Expand
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2005
2005
ABSTRACT The in vitro activity of DX-619, a new des-F(6)-quinolone, was tested against staphylococci and compared to those of… Expand
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Review
2005
Review
2005
The development of resistance in the major pathogenic Gram-positive genera Staphylococcus and Streptococccus has led to the need… Expand