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Quinolones

Known as: Quinolinones, Oxoquinolines, Quinolones [Chemical/Ingredient] 
A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.
National Institutes of Health

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2-heptyl-3-hydroxy-4-quinolone3-hydroxyquinolin-2(1H)-one349U857-piperazinylquinolone
In BloodLevofloxacinMoxifloxacin hydrochlorideagonists

Papers overview

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Review
2000
Review
2000
Quinolone-induced QT interval prolongation: a not-so-unexpected class effect.
Sir, I read with great interest Dr Peter Ball’s recent leading article on quinolone-induced QT interval prolongation. The author… 
2000
2000
Taste masking oral quinolone liquid preparations using ion-exchange resin
(57) Abstract: The present invention is an ion-exchange resin as a carrier (e.g., methacrylic acid polymer crosslinked with… 
1997
1997
Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugs.
Topoisomerase II is the cytotoxic target for a number of clinically relevant antineoplastic drugs. Despite the fact that these… 
1996
1996
SUSCEPTIBILITY OF ANAEROBIC BACTERIA TO TROVAFLOXACIN: COMPARISON WITH OTHER QUINOLONES AND NON‐QUINOLONE ANTIBIOTICS
SUSCEPTIBILITY OF ANAEROBIC BACTERIA TO TROVAFLOXACIN: COMPARISON WITH OTHER QUINOLONES AND NON-QUINOLONE ANTIBIOTICS S. Spangler… 
1994
1994
Synthesis and antitumour activities of tetracyclic quinolone antineoplastic agents.
DNA topoisomerases, found in all prokaryotic and eukaryotic cells, play a key role in controlling the topological state of DNA… 
Review
1989
Review
1989
Clinical Significance of Antibiotic Tissue Penetration
SummaryThe concentrations achieved by a particular antibiotic in serum and tissues can be predicted from pharmacokinetic data… 
1986
1986
Acute Hemodynamic Effects of a New Positive Inotropic Agent, 3,4-Dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone (OPC-8212), in Conscious and Anesthetized Dogs
Summary: The acute hemodynamic effects of a new cardiotonic agent, OPC-8212 (a 1H-quinolinone derivative), were studied in six… 
1985
1985
Synthesis and antiallergic activity of some quinolinones and imidazoquinolinones.
A group of 1,4-dihydro-4-oxoquinoline-2- and -3-carboxylic acid esters with nitrogen functionality at the 8-position was… 
1984
1984
Studies on positive inotropic agents. I. Synthesis of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone and related compounds.
Many (1-piperazinyl)-2 (1H)-quinolinone derivatives were synthesized and examined for positive inotropic activities on the canine… 
1967
1967
Studies on the mode of action of quinolone and pyridone coccidiostats.
The primary action of the anticoccidial drugs methyl benzoquate, buquinolate, and meticlorpindol is to prevent the growth of…