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Occurrence and Detection of AmpC Beta-Lactamases among Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis Isolates at a Veterans Medical Center
- P. Coudron, E. S. Moland, K. Thomson
- Biology, Medicine
- Journal of Clinical Microbiology
- 1 May 2000
ABSTRACT AmpC beta-lactamases are cephalosporinases that confer resistance to a wide variety of β-lactam drugs and that may thereby create serious therapeutic problems. Although reported with… Expand
AmpC Disk Test for Detection of Plasmid-Mediated AmpC β-Lactamases in Enterobacteriaceae Lacking Chromosomal AmpC β-Lactamases
- J. Black, E. S. Moland, K. Thomson
- Biology
- Journal of Clinical Microbiology
- 1 July 2005
ABSTRACT Although plasmid-mediated AmpC β-lactamases were first reported in the late 1980s, many infectious disease personnel remain unaware of their clinical importance. These enzymes are typically… Expand
β-Lactamases Responsible for Resistance to Expanded-Spectrum Cephalosporins in Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis Isolates Recovered in South Africa
- J. Pitout, K. Thomson, N. Hanson, A. F. Ehrhardt, E. S. Moland, C. Sanders
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 June 1998
ABSTRACT Although resistance to the expanded-spectrum cephalosporins among members of the family Enterobacteriaceae lacking inducible β-lactamases occurs virtually worldwide, little is known about… Expand
Detection of extended-spectrum-beta-lactamase-producing members of the family Enterobacteriaceae with Vitek ESBL test.
- C. Sanders, A. Barry, +5 authors R. Mulder
- Biology, Medicine
- Journal of clinical microbiology
- 1 December 1996
A three-phase analysis of the Vitek ESBL test and a double-disk (2 disk) test was performed to assess their ability to detect extended-spectrum beta-lactamases (ESBLs) in members of the family… Expand
Molecular characterization of a multiply resistant Klebsiella pneumoniae encoding ESBLs and a plasmid-mediated AmpC.
- N. Hanson, K. Thomson, E. S. Moland, C. Sanders, G. Berthold, R. Penn
- Biology, Medicine
- The Journal of antimicrobial chemotherapy
- 1 September 1999
Organisms encoding multiple antibiotic resistance genes are becoming increasingly prevalent. In this report we describe a multiply resistant Klebsiella pneumoniae which possesses at least five… Expand
Occurrence and detection of extended-spectrum beta-lactamases in members of the family Enterobacteriaceae at a veterans medical center: seek and you may find.
- P. Coudron, E. S. Moland, C. Sanders
- Medicine, Biology
- Journal of clinical microbiology
- 1 October 1997
A total of 907 consecutive isolates of members of the family Enterobacteriaceae recovered during a 20-week period were tested for production of extended-spectrum beta-lactamases (ESBLs) by the… Expand
Plasmid-Mediated Carbapenem-Hydrolyzing Enzyme KPC-2 in an Enterobacter sp
- Ashfaque Hossain, M. Ferraro, +6 authors N. Hanson
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 November 2004
ABSTRACT A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a… Expand
Discovery of CTX-M-Like Extended-Spectrum β-Lactamases in Escherichia coli Isolates from Five U.S. States
- E. S. Moland, J. Black, A. Hossain, N. Hanson, K. Thomson, S. Pottumarthy
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 July 2003
The most commonly reported extended-spectrum β-lactamases (ESBLs) in U.S. isolates of Escherichia coli are TEM and SHV derived (2). CTX-M ESBLs have been reported elsewhere, mostly for clinical… Expand
Kinetics Study of KPC-3, a Plasmid-Encoded Class A Carbapenem-Hydrolyzing β-Lactamase
- J. Alba, Y. Ishii, Kenneth Thomson, E. S. Moland, K. Yamaguchi
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 November 2005
ABSTRACT The kinetic activity of KPC-3, a plasmid-encoded class A carbapenemase, was studied. It hydrolyzed penicillins, cephalosporins, carbapenems, and even sulbactam. The best substrate was… Expand
Ability of the VITEK 2 Advanced Expert System To Identify β-Lactam Phenotypes in Isolates of Enterobacteriaceae andPseudomonas aeruginosa
- C. Sanders, M. Peyret, +4 authors W. Sanders
- Biology, Medicine
- Journal of Clinical Microbiology
- 1 February 2000
ABSTRACT The Advanced Expert System (AES) was used in conjunction with the VITEK 2 automated antimicrobial susceptibility test system to ascertain the β-lactam phenotypes of 196 isolates of the… Expand