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Pyrrolidines

Known as: Pyrrolidines [Chemical/Ingredient] 
National Institutes of Health

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1-benzylpyrrolidine1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide2,4-methanopyrrolidine-2,4-dicarboxylate2-oxo-1-pyrrolidine acetic acid
antagonists & inhibitorschemical synthesis

Papers overview

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Highly Cited
2016
Highly Cited
2016
Ligand-Enabled γ-C(sp(3))-H Olefination of Amines: En Route to Pyrrolidines.
Pd(II)-catalyzed olefination of γ-C(sp(3))-H bonds of triflyl (Tf) and 4-nitrobenzenesulfonyl (Ns) protected amines is achieved… 
Highly Cited
2014
Highly Cited
2014
A Regio- and Stereoselective ω-Transaminase/Monoamine Oxidase Cascade for the Synthesis of Chiral 2,5-Disubstituted Pyrrolidines
Biocatalytic approaches to the synthesis of optically pure chiral amines, starting from simple achiral building blocks, are… 
Highly Cited
2011
Highly Cited
2011
Ruthenium-catalyzed conversion of levulinic acid to pyrrolidines by reductive amination.
The current global mass consumption of non-renewable fossil fuels is forcing academic and industrial scientists to find… 
Highly Cited
2010
Highly Cited
2010
Dynamic kinetic asymmetric synthesis of substituted pyrrolidines from racemic cyclopropanes and aldimines: reaction development and mechanistic insights.
An enantioselective preparation of 2,5-cis-disubstituted pyrrolidines has been achieved via a dynamic kinetic asymmetric… 
Review
2007
Review
2007
Intramolecular aminopalladation of alkenes as a key step to pyrrolidines and related heterocycles.
Palladium catalysis for the intramolecular amination of alkenes is a powerful approach in heterocycle synthesis. The initial… 
Highly Cited
2007
Highly Cited
2007
Pyrrolidine and piperidine formation via copper(II) carboxylate-promoted intramolecular carboamination of unactivated olefins: diastereoselectivity and mechanism.
An expanded substrate scope and in-depth analysis of the reaction mechanism of the copper(II) carboxylate-promoted intramolecular… 
Review
2007
Review
2007
Palladium-Catalyzed Carboetherification and Carboamination Reactions of γ-Hydroxy- and γ-Aminoalkenes for the Synthesis of Tetrahydrofurans and Pyrrolidines.
Substituted tetrahydrofuran and pyrrolidine moieties are displayed in a wide range of interesting biologically active molecules… 
Highly Cited
2006
Highly Cited
2006
sp3 C-H bond arylation directed by amidine protecting group: alpha-arylation of pyrrolidines and piperidines.
A new ruthenium-catalyzed direct sp3 C-H to C-C bond transformation is disclosed. Specifically, a method for the alpha-arylation… 
Highly Cited
2003
Highly Cited
2003
Synthesis, antimicrobial and antifungal activity of a new class of spiro pyrrolidines.
Highly Cited
2002
Highly Cited
2002
Brønsted acid-catalyzed intramolecular hydroamination of protected alkenylamines. Synthesis of pyrrolidines and piperidines.
[reaction: see text]. The cyclization of aminoalkenes bearing an electron-withdrawing group on the nitrogen atom was catalyzed by… 
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