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Pyrrolidines

Known as: Pyrrolidines [Chemical/Ingredient] 
National Institutes of Health

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1-benzylpyrrolidine1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide2,4-methanopyrrolidine-2,4-dicarboxylate2-oxo-1-pyrrolidine acetic acid
antagonists & inhibitorschemical synthesis

Papers overview

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2015
2015
Silver(I)-Catalyzed Enantioselective Desymmetrization of Cyclopentenediones: Access to Highly Functionalized Bicyclic Pyrrolidines.
A highly enantioselective desymmetrization of prochiral cyclopentenediones via Ag(I)-catalyzed asymmetric 1,3-dipolar… 
Highly Cited
2014
Highly Cited
2014
Copper-Catalyzed Alkene Diamination: Synthesis of Chiral 2-Aminomethyl Indolines and Pyrrolidines.
Chiral vicinal diamines, including 2-aminomethyl indolines and pyrrolidines, are useful as ligands for catalytic asymmetric… 
Highly Cited
2013
Highly Cited
2013
Addition of organometallic reagents to chiral N-methoxylactams: enantioselective syntheses of pyrrolidines and piperidines.
Enantioselective iridium-catalyzed allylic substitutions were used to prepare N-allyl hydroxamic acid derivatives that were… 
2010
2010
A facile asymmetric synthesis of either enantiomer of 2-substituted pyrrolidines.
A new and general method for asymmetric synthesis of either enantiomer of 2-substituted pyrrolidines from a single starting… 
2010
2010
Diastereoselective preparation of azetidines and pyrrolidines.
Iodine-mediated cyclization of homoallyl amines at room temperature delivered cis-2,4-azetidine through a 4-exo trig cyclization… 
Highly Cited
2007
Highly Cited
2007
Bisphosphine-catalyzed mixed double-Michael reactions: asymmetric synthesis of oxazolidines, thiazolidines, and pyrrolidines.
Bisphosphine-catalyzed mixed double-Michael reactions have been developed to afford β-amino carbonyl derivatives of oxazolidines… 
2007
2007
Stereoselective synthesis of beta-1-C-substituted 1,4-dideoxy-1,4-imino-D-galactitols and evaluation as UDP-galactopyranose mutase inhibitors.
Highly Cited
2006
Highly Cited
2006
Scandium triflate catalyzed cycloaddition of imines with 1,1-cyclopropanediesters: efficient and diastereoselective synthesis of multi-substituted pyrrolidines.
A tandem ring-opening-cyclization reaction of cyclopropanes with imines in the presence of 5 mol% of scandium triflate was… 
Highly Cited
2005
Highly Cited
2005
Diastereoselective synthesis of pyrrolidines via the Yb(OTf)3 catalyzed three-component reaction of aldehydes, amines, and 1,1-cyclopropanediesters.
[Chemical reaction: see text] Aldimines, generated in situ by the reaction of primary amines or anilines with aldehydes, undergo… 
Highly Cited
2001
Highly Cited
2001
Catalytic direct asymmetric Michael reactions: taming naked aldehyde donors.
[reaction--see text] Direct catalytic enantio- and diastereoselective Michael addition reactions of unmodified aldehydes to nitro… 
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