DNA Sequence Rearrangement

Known as: Rearrangement, Rearrangements 
Any process affecting a DNA sequence that results in the gain, loss or exchange of DNA between chromosomes and/or autonomous replicons.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Genomic analysis has greatly influenced the diagnosis and clinical management of patients affected by diverse forms of… (More)
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Review
2016
Review
2016
Genetic variation associated with disease often appears in non-coding parts of the genome. Understanding the mechanisms by which… (More)
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Highly Cited
2011
Highly Cited
2011
Cancer is driven by somatically acquired point mutations and chromosomal rearrangements, conventionally thought to accumulate… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental… (More)
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Highly Cited
2009
Highly Cited
2009
Multiple somatic rearrangements are often found in cancer genomes; however, the underlying processes of rearrangement and their… (More)
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Highly Cited
2007
Highly Cited
2007
The prevailing mechanism for recurrent and some nonrecurrent rearrangements causing genomic disorders is nonallelic homologous… (More)
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Highly Cited
2004
Highly Cited
2004
As genomes evolve, they undergo large-scale evolutionary processes that present a challenge to sequence comparison not posed by… (More)
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Review
2002
Review
2002
An increasing number of human diseases are recognized to result from recurrent DNA rearrangements involving unstable genomic… (More)
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Review
1998
Review
1998
Molecular medicine began with Pauling's seminal work, which recognized sickle-cell anemia as a molecular disease, and with Ingram… (More)
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Highly Cited
1992
Highly Cited
1992
We have generated mice that carry a germline mutation in which a large portion of the RAG-2 coding region is deleted. Homozygous… (More)
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