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Caspase-1

Known as: Interleukin 1beta Converting Enzyme, IL 1 beta Convertase, Interleukin 1-Beta Convertase 
A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically… 
National Institutes of Health

Related topics

Related topics

25 relations
ApoptosisCASP1 geneCASP1 wt AlleleCaspase Cascade Pathway

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Procaspase-1

Papers overview

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Highly Cited
2010
Highly Cited
2010
IL-33 is upregulated in colonocytes of ulcerative colitis.
Highly Cited
2000
Highly Cited
2000
In vivo induction of cardiac Purkinje fiber differentiation by coexpression of preproendothelin-1 and endothelin converting enzyme-1.
The rhythmic heart beat is coordinated by electrical impulses transmitted from Purkinje fibers of the cardiac conduction system… 
Highly Cited
2000
Highly Cited
2000
Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes.
Angiotensin-converting enzyme (ACE) inhibitors reduce the risk of recurrent myocardial infarction in patients with left… 
Highly Cited
1999
Highly Cited
1999
Early induction of apoptosis in androgen‐independent prostate cancer cell line by FTY720 requires caspase‐3 activation
We previously reported that FTY720, a metabolite from Isaria sinclairii, induced some cancer cells to undergo apoptosis, and that… 
Highly Cited
1996
Highly Cited
1996
Type I Insulin-like Growth Factor Receptor Activation Regulates Apoptotic Proteins*
Activation of the type I insulin-like growth factor receptor (IGF-IR) blocks osmotic mediated programmed cell death (PCD) in… 
Highly Cited
1996
Highly Cited
1996
Intracellular redox changes during apoptosis.
In the current paradigm for apoptotic cell death, the activity of a family of proteases related to interleukin 1-beta converting… 
Highly Cited
1996
Highly Cited
1996
Sequential activation of three distinct ICE‐like activities in Fas‐ligated Jurkat cells
Review
1995
Review
1995
Role of multiple cellular proteases in the execution of programmed cell death
Highly Cited
1994
Highly Cited
1994
Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase.
The cDNA encoding human stratum corneum chymotryptic enzyme (SCCE); an epidermal serine-proteinase which was recently purified… 
Highly Cited
1994
Highly Cited
1994
A Biological Sensor for Iron Available to Bacteria in Their Habitats on Plant Surfaces
A sensor responsive to iron was constructed by fusing a promoterless ice nucleation activity gene (inaZ) to an iron-regulated… 
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