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CASP1 gene

Known as: INTERLEUKIN 1-BETA CONVERTASE, caspase 1, ICE 
This gene plays a role in apoptosis, inflammation, septic shock, and wound healing.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BackgroundEarly HIV-1 infection causes massive CD4+ T cell death in the gut and translocation of bacteria into the circulation… 
2012
2012
Embryonic stem cell (ESC)‐based therapy is a promising treatment for neurodegenerative diseases. But there is always a risk of… 
2011
2011
Borrelia burgdorferi spirochetes cause Lyme disease, which can result in severe clinical symptoms such as multiple joint… 
Review
2011
Review
2011
Pathogens are detected by a variety of innate immune sensors in host cells leading to rapid induction of cell autonomous… 
2008
2008
Anthrax lethal toxin (LT) rapidly kills macrophages from certain mouse strains in a mechanism dependent on the breakdown of… 
2006
2006
Background  Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by elevated serum levels of IgE. AD is… 
Highly Cited
2004
Highly Cited
2004
Caspase-1 is a cysteine protease composed by two 20-kDa and two 10-kDa subunits that processes pro-IL-1β and pro-IL-18 to their… 
2003
2003
2003
Abstract Salmonella enteritidis (SE) contamination of poultry products is a major cause of food‐borne disease worldwide. Caspase…