CLSPN gene

Known as: CLSPN, Claspin Gene, claspin 
This gene is involved in checkpoint mediated cell cycle arrest.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Mammalian Timeless is a multifunctional protein that performs essential roles in the circadian clock, chromosome cohesion, DNA… (More)
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Highly Cited
2009
Highly Cited
2009
mammals f Box Protein substrates Biological functions of substrates kinase(s) Fbxw1/βTRCP1 (Fbxw11/ β-TrCP2) Atf4 txn factor… (More)
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Highly Cited
2008
Highly Cited
2008
In response to DNA damage in G2, mammalian cells must avoid entry into mitosis and instead initiate DNA repair. Here, we show… (More)
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Highly Cited
2007
Highly Cited
2007
UV-induced DNA damage stalls DNA replication forks and activates the intra-S checkpoint to inhibit replicon initiation. In… (More)
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Highly Cited
2007
Highly Cited
2007
Here, we show that the human homologue of the Caenorhabditis elegans biological clock protein CLK-2 (HCLK2) associates with the S… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Checkpoint signaling pathways are of crucial importance for the maintenance of genomic integrity. Within these… (More)
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Highly Cited
2005
Highly Cited
2005
The RecQ helicase Sgs1p forms a complex with the type 1 DNA topoisomerase Top3p that resolves double Holliday junctions resulting… (More)
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Highly Cited
2004
Highly Cited
2004
The ataxia telangiectasia-mutated (ATM) and Rad3-related kinase (ATR) is a central component of the cell cycle checkpoint… (More)
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Highly Cited
2004
Highly Cited
2004
Claspin is necessary for the ATR-dependent activation of Chk1 in Xenopus egg extracts containing incompletely replicated DNA. ATR… (More)
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Highly Cited
2003
Highly Cited
2003
Claspin is required for the ATR-dependent activation of Chk1 in Xenopus egg extracts containing incompletely replicated DNA. We… (More)
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