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Negative Regulation of Cell Cycle
Known as:
negative regulation of progression through cell cycle
, downregulation of progression through cell cycle
, Cell Cycle Inhibition
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An interruption in the periodic biochemical and structural events occurring during proliferation of cells such as in tissue culture; the cycle is…
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National Institutes of Health
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Related topics
Related topics
50 relations
ARRY 520
AZD 4877
CDK inhibitor AT7519M
CDK2/5/9 Inhibitor CYC065
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Broader (1)
biological control
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest
Zhuo Xian Meng
,
J. Nie
,
+7 authors
Xiao Han
Diabetologia
2008
Corpus ID: 24986952
Aims/hypothesisLiver X receptors (LXRs) are important transcriptional regulators of lipid homeostasis and proliferation in…
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Highly Cited
2005
Highly Cited
2005
Clinical implications of aberrant DNA methylation patterns in acute myelogenous leukemia
O. Galm
,
S. Wilop
,
+4 authors
R. Osieka
Annals of Hematology
2005
Corpus ID: 9464999
Hypermethylation of CpG islands near gene promoter regions is associated with transcriptional inactivation and represents an…
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Highly Cited
2003
Highly Cited
2003
Differential regulation of TGF-β signaling through Smad2, Smad3 and Smad4
A. Kretschmer
,
Kristin Moepert
,
S. Dames
,
Maria Sternberger
,
Joerg Kaufmann
,
A. Klippel
Oncogene
2003
Corpus ID: 45201132
Smad transcription factors mediate the growth inhibitory effect of transforming growth factor-β (TGF-β) in many cell types…
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Highly Cited
2002
Highly Cited
2002
Modulation of cell proliferation and cell cycle regulators by vitamin E in human prostate carcinoma cell lines.
V. Venkateswaran
,
N. Fleshner
,
L. Klotz
Journal of Urology
2002
Corpus ID: 20440644
Highly Cited
2001
Highly Cited
2001
IGF-II down regulation associated cell cycle arrest in colon cancer cells exposed to phenolic antioxidant ellagic acid.
Bhagavathi A. Narayanan
,
Gian G. Re
Anticancer Research
2001
Corpus ID: 6373472
Altered cell and tissue differentiation is characteristic of premalignant lesions long before they become invasive and metastatic…
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Highly Cited
2000
Highly Cited
2000
Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization
H. Rizos
,
Artur P. Darmanian
,
G. J. Mann
,
R. Kefford
Oncogene
2000
Corpus ID: 21180004
The INK4a/ARF locus encodes two distinct tumour suppressors, p16INK4a and p14ARF, that regulate cell cycle progression via the…
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Highly Cited
2000
Highly Cited
2000
The molecular chaperone Cdc37 is required for Ste11 function and pheromone‐induced cell cycle arrest
T. Abbas-Terki
,
O. Donzé
,
D. Picard
FEBS Letters
2000
Corpus ID: 31080251
Highly Cited
1995
Highly Cited
1995
Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase.
T. Herzinger
,
J. Funk
,
K. Hillmer
,
D. Eick
,
Wolff Da
,
P. Kind
Oncogene
1995
Corpus ID: 34463312
In response to genotoxic stress, cell cycle progression can be arrested at certain checkpoints which serve to maintain genomic…
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Highly Cited
1994
Highly Cited
1994
Lyn tyrosine kinase signals cell cycle arrest but not apoptosis in B-lineage lymphoma cells.
R. Scheuermann
,
E. Racila
,
+5 authors
J. Uhr
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 31985502
Signal transduction initiated by binding of antibodies to cell surface molecules can have an important impact on the growth of…
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Highly Cited
1993
Highly Cited
1993
Investigation of the role of G1/S cell cycle mediators in cellular senescence.
Cynthia A. Afshari
,
Cynthia A. Afshari
,
+9 authors
J. Barrett
Experimental Cell Research
1993
Corpus ID: 25656069
Cellular senescence is a state of irreversible cell cycle arrest in which normal cells at the end of their lifespan fail to enter…
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