Skip to search formSkip to main contentSkip to account menu

Negative Regulation of Cell Cycle

Known as: negative regulation of progression through cell cycle, downregulation of progression through cell cycle, Cell Cycle Inhibition 
An interruption in the periodic biochemical and structural events occurring during proliferation of cells such as in tissue culture; the cycle is… 
National Institutes of Health

Related topics

Related topics

50 relations
ARRY 520AZD 4877CDK inhibitor AT7519MCDK2/5/9 Inhibitor CYC065

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest
Aims/hypothesisLiver X receptors (LXRs) are important transcriptional regulators of lipid homeostasis and proliferation in… 
Highly Cited
2005
Highly Cited
2005
Clinical implications of aberrant DNA methylation patterns in acute myelogenous leukemia
Hypermethylation of CpG islands near gene promoter regions is associated with transcriptional inactivation and represents an… 
Highly Cited
2003
Highly Cited
2003
Differential regulation of TGF-β signaling through Smad2, Smad3 and Smad4
Smad transcription factors mediate the growth inhibitory effect of transforming growth factor-β (TGF-β) in many cell types… 
Highly Cited
2002
Highly Cited
2002
Modulation of cell proliferation and cell cycle regulators by vitamin E in human prostate carcinoma cell lines.
Highly Cited
2001
Highly Cited
2001
IGF-II down regulation associated cell cycle arrest in colon cancer cells exposed to phenolic antioxidant ellagic acid.
Altered cell and tissue differentiation is characteristic of premalignant lesions long before they become invasive and metastatic… 
Highly Cited
2000
Highly Cited
2000
Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization
The INK4a/ARF locus encodes two distinct tumour suppressors, p16INK4a and p14ARF, that regulate cell cycle progression via the… 
Highly Cited
2000
Highly Cited
2000
The molecular chaperone Cdc37 is required for Ste11 function and pheromone‐induced cell cycle arrest
Highly Cited
1995
Highly Cited
1995
Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase.
In response to genotoxic stress, cell cycle progression can be arrested at certain checkpoints which serve to maintain genomic… 
Highly Cited
1994
Highly Cited
1994
Lyn tyrosine kinase signals cell cycle arrest but not apoptosis in B-lineage lymphoma cells.
Signal transduction initiated by binding of antibodies to cell surface molecules can have an important impact on the growth of… 
Highly Cited
1993
Highly Cited
1993
Investigation of the role of G1/S cell cycle mediators in cellular senescence.
Cellular senescence is a state of irreversible cell cycle arrest in which normal cells at the end of their lifespan fail to enter… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)