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Cell Cycle Checkpoints

Known as: Checkpoint, Checkpoints, Cell Cycle, Cell Cycle Checkpoint 
Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and… 
National Institutes of Health

Related topics

Related topics

50 relations
ATRIP protein, humanBABAM1 geneBABAM1 protein, humanBRCA1 gene

Narrower (3)

G2/M checkpointmeiotic cell cycle checkpointmitotic cell cycle checkpoint

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
DNA damage induces Chk1‐dependent centrosome amplification
Centrosomal abnormalities are frequently observed in cancers and in cells with defective DNA repair. Here, we used light and… 
Review
2005
Review
2005
Geminin-Cdt1 balance is critical for genetic stability.
Highly Cited
2002
Highly Cited
2002
Cnd2 has dual roles in mitotic condensation and interphase
Chromosome condensation requires condensin, which comprises five subunits. Two of these subunits—both being structural… 
Review
2000
Review
2000
The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more.
Highly Cited
2000
Highly Cited
2000
Dynein Is a Transient Kinetochore Component Whose Binding Is Regulated by Microtubule Attachment, Not Tension
Cytoplasmic dynein is the only known kinetochore protein capable of driving chromosome movement toward spindle poles. In… 
Highly Cited
1997
Highly Cited
1997
Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae
Saccharomyces cerevisiae, like most eucaryotic cells, can prevent the onset of anaphase until chromosomes are properly aligned on… 
Highly Cited
1997
Highly Cited
1997
Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner.
Replication protein A (RPA) is required for both DNA replication and nucleotide excision repair. Previous studies have shown that… 
Highly Cited
1996
Highly Cited
1996
Chemical induction of mitotic checkpoint override in mammalian cells results in aneuploidy following a transient tetraploid state.
Highly Cited
1994
Highly Cited
1994
Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells
The protein kinase inhibitor 2-aminopurine induces checkpoint override and mitotic exit in BHK cells which have been arrested in… 
Highly Cited
1993
Highly Cited
1993
RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae.
Exposure of the yeast Saccharomyces cerevisiae to ultraviolet (UV) light, the UV-mimetic chemical 4-nitroquinoline-1-oxide (4NQO… 
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