Skip to search formSkip to main contentSkip to account menu

Cell Cycle Checkpoints

Known as: Checkpoint, Checkpoints, Cell Cycle, Cell Cycle Checkpoint 
Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and… 
National Institutes of Health

Related topics

Related topics

50 relations
ATRIP protein, humanBABAM1 geneBABAM1 protein, humanBRCA1 gene

Narrower (3)

G2/M checkpointmeiotic cell cycle checkpointmitotic cell cycle checkpoint

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer.
BACKGROUND Patients with advanced squamous-cell non-small-cell lung cancer (NSCLC) who have disease progression during or after… 
Review
2012
Review
2012
The blockade of immune checkpoints in cancer immunotherapy
  • D. Pardoll
  • Nature Reviews Cancer
  • 2012
  • Corpus ID: 19190366
Among the most promising approaches to activating therapeutic antitumour immunity is the blockade of immune checkpoints. Immune… 
Highly Cited
2006
Highly Cited
2006
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Ionizing radiation represents the most effective therapy for glioblastoma (World Health Organization grade IV glioma), one of the… 
Review
2004
Review
2004
Cell-cycle checkpoints and cancer
All life on earth must cope with constant exposure to DNA-damaging agents such as the Sun's radiation. Highly conserved DNA… 
Review
2004
Review
2004
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.
DNA damage is a relatively common event in the life of a cell and may lead to mutation, cancer, and cellular or organismic death… 
Review
2001
Review
2001
Cell cycle checkpoint signaling through the ATM and ATR kinases.
  • R. Abraham
  • Genes & development
  • 2001
  • Corpus ID: 8243401
The genomes of eukaryotic cells are under continuous assault by environmental agents (e.g., UV light and reactive chemicals) as… 
Review
1996
Review
1996
Cancer Cell Cycles
Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly… 
Review
1996
Review
1996
Cell Cycle Checkpoints: Preventing an Identity Crisis
Cell cycle checkpoints are regulatory pathways that control the order and timing of cell cycle transitions and ensure that… 
Review
1994
Review
1994
Cell cycle control and cancer.
Multiple genetic changes occur during the evolution of normal cells into cancer cells. This evolution is facilitated in cancer… 
Highly Cited
1992
Highly Cited
1992
Wild-type p53 is a cell cycle checkpoint determinant following irradiation.
Cell cycle checkpoints appear to contribute to an increase in cell survival and a decrease in abnormal heritable genetic changes… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License