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Cell Cycle Checkpoints

Known as: Checkpoint, Checkpoints, Cell Cycle, Cell Cycle Checkpoint 
Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and… Expand
National Institutes of Health

Related topics

Related topics

50 relations
ATRIP protein, humanBABAM1 geneBABAM1 protein, humanBRCA1 gene
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Narrower (3)

G2/M checkpointmeiotic cell cycle checkpointmitotic cell cycle checkpoint

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Innate Lymphoid Cells: 10 Years On
Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified antigen receptors expressed on T cells… Expand
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Review
2018
Review
2018
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy.
Immune checkpoint blockade is able to induce durable responses across multiple types of cancer, which has enabled the oncology… Expand
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Review
2018
Review
2018
PD‐1 Blockade with Cemiplimab in Advanced Cutaneous Squamous‐Cell Carcinoma
Background No systemic therapies have been approved for the treatment of advanced cutaneous squamous‐cell carcinoma. This cancer… Expand
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Review
2018
Review
2018
Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial.
BACKGROUND Immune checkpoint blockade therapy has shown promising results in patients with advanced hepatocellular carcinoma. We… Expand
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Review
2018
Review
2018
Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations
Melanoma, a skin cancer associated with high mortality rates, is highly radio- and chemotherapy resistant but can also be very… Expand
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Review
2018
Review
2018
Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors.
Although T lymphocytes have long been appreciated for their role in the immunosurveillance of cancer, it has been the realization… Expand
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Review
2018
Review
2018
Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC)
Immunotherapy is among the most rapidly evolving treatment strategies in oncology. The therapeutic potential of immune-checkpoint… Expand
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Review
2018
Review
2018
Cancer immunotherapy efficacy and patients' sex: a systematic review and meta-analysis.
BACKGROUND Despite the acknowledged sex-related dimorphism in immune system response, little is known about the effect of… Expand
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Review
2018
Review
2018
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
The IL-6/JAK/STAT3 pathway is aberrantly hyperactivated in many types of cancer, and such hyperactivation is generally associated… Expand
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Review
2018
Review
2018
Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline.
Purpose To increase awareness, outline strategies, and offer guidance on the recommended management of immune-related adverse… Expand
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