Cell Cycle Checkpoints

Known as: Checkpoint, Checkpoints, Cell Cycle, Cell Cycle Checkpoint 
Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and… (More)

Topic mentions per year

Topic mentions per year

1979-2017
020040019792017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
INTRODUCTION Immune checkpoints are regulatory pathways induced in activated T lymphocytes that regulate antigen responsiveness… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
DNA-damage signaling utilizes a multitude of posttranslational modifiers as molecular switches to regulate cell-cycle checkpoints… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The ATM (ataxia-telangiectasia mutated) and ATR (ataxia-telangiectasia and Rad3-related) kinases respond to DNA damage by… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Checkpoint kinase (Chk)1 is an evolutionarily conserved protein kinase that was first identified in fission yeast as an essential… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
To maintain genomic stability following DNA damage, multicellular organisms activate checkpoints that induce cell cycle arrest or… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
G1/S and G2/M cell cycle checkpoints maintain genomic stability in eukaryotes in response to genotoxic stress. We report here… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Germline mutations of the Brca1 tumor suppressor gene predispose women to breast and ovarian cancers. To study mechanisms… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Computer analysis of a conserved domain, BRCT, first described at the carboxyl terminus of the breast cancer protein BRCA1, a p53… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Cell cycle checkpoints can enhance cell survival and limit mutagenic events following DNA damage. Primary murine fibroblasts… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Cell cycle checkpoints appear to contribute to an increase in cell survival and a decrease in abnormal heritable genetic changes… (More)
  • figure 1
  • figure 3
  • figure 4
Is this relevant?