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Cell Cycle Checkpoints
Known as:
Checkpoint
, Checkpoints, Cell Cycle
, Cell Cycle Checkpoint
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Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and…
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National Institutes of Health
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Related topics
Related topics
50 relations
ATRIP protein, human
BABAM1 gene
BABAM1 protein, human
BRCA1 gene
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Narrower (3)
G2/M checkpoint
meiotic cell cycle checkpoint
mitotic cell cycle checkpoint
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Oncogene addiction versus oncogene amnesia: perhaps more than just a bad habit?
D. Felsher
Cancer Research
2008
Corpus ID: 16984391
Cancer is a multistep process whereby genetic events that result in the activation of proto-oncogenes or the inactivation of…
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Highly Cited
2007
Highly Cited
2007
DNA damage induces Chk1‐dependent centrosome amplification
E. Bourke
,
H. Dodson
,
+5 authors
C. Morrison
EMBO Reports
2007
Corpus ID: 35898524
Centrosomal abnormalities are frequently observed in cancers and in cells with defective DNA repair. Here, we used light and…
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Highly Cited
2005
Highly Cited
2005
Activation of Ataxia Telangiectasia-mutated DNA Damage Checkpoint Signal Transduction Elicited by Herpes Simplex Virus Infection*
Noriko Shirata
,
A. Kudoh
,
+7 authors
T. Tsurumi
Journal of Biological Chemistry
2005
Corpus ID: 45804278
Eukaryotic cells are equipped with machinery to monitor and repair damaged DNA. Herpes simplex virus (HSV) DNA replication occurs…
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Highly Cited
2002
Highly Cited
2002
Cnd2 has dual roles in mitotic condensation and interphase
Nobuki Aono
,
T. Sutani
,
T. Tomonaga
,
S. Mochida
,
M. Yanagida
Nature
2002
Corpus ID: 4332524
Chromosome condensation requires condensin, which comprises five subunits. Two of these subunits—both being structural…
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Highly Cited
1997
Highly Cited
1997
RAD9, RAD17, and RAD24 are required for S phase regulation in Saccharomyces cerevisiae in response to DNA damage.
A. Paulovich
,
R. U. Margulies
,
B. Garvik
,
L. Hartwell
Genetics
1997
Corpus ID: 20515310
We have previously shown that a checkpoint dependent on MEC1 and RAD53 slows the rate of S phase progression in Saccharomyces…
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Highly Cited
1997
Highly Cited
1997
Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae
Yanchang Wang
,
Daniel J. Burke
Molecular and Cellular Biology
1997
Corpus ID: 41104619
Saccharomyces cerevisiae, like most eucaryotic cells, can prevent the onset of anaphase until chromosomes are properly aligned on…
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Highly Cited
1997
Highly Cited
1997
Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner.
Natalia A. Abramova
,
Jackie Russell
,
Jackie Russell
,
M. Botchan
,
Rong Li
Proceedings of the National Academy of Sciences…
1997
Corpus ID: 34396971
Replication protein A (RPA) is required for both DNA replication and nucleotide excision repair. Previous studies have shown that…
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Highly Cited
1996
Highly Cited
1996
Chemical induction of mitotic checkpoint override in mammalian cells results in aneuploidy following a transient tetraploid state.
P. Andreassen
,
S. Martineau
,
R. Margolis
Mutation research
1996
Corpus ID: 19773660
Highly Cited
1994
Highly Cited
1994
Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells
P. Andreassen
,
Robert L. Margolis
Journal of Cell Biology
1994
Corpus ID: 2555065
The protein kinase inhibitor 2-aminopurine induces checkpoint override and mitotic exit in BHK cells which have been arrested in…
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Highly Cited
1993
Highly Cited
1993
RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae.
W. Siede
,
Andrew S. Friedberg
,
E. Friedberg
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 22569407
Exposure of the yeast Saccharomyces cerevisiae to ultraviolet (UV) light, the UV-mimetic chemical 4-nitroquinoline-1-oxide (4NQO…
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