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Cell Cycle Checkpoints

Known as: Checkpoint, Checkpoints, Cell Cycle, Cell Cycle Checkpoint 
Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and… 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Patients with advanced squamous-cell non-small-cell lung cancer (NSCLC) who have disease progression during or after… 
Review
2012
Review
2012
  • D. Pardoll
  • Nature Reviews Cancer
  • 2012
  • Corpus ID: 19190366
Among the most promising approaches to activating therapeutic antitumour immunity is the blockade of immune checkpoints. Immune… 
Highly Cited
2006
Highly Cited
2006
Ionizing radiation represents the most effective therapy for glioblastoma (World Health Organization grade IV glioma), one of the… 
Review
2004
Review
2004
All life on earth must cope with constant exposure to DNA-damaging agents such as the Sun's radiation. Highly conserved DNA… 
Review
2004
Review
2004
DNA damage is a relatively common event in the life of a cell and may lead to mutation, cancer, and cellular or organismic death… 
Review
2001
Review
2001
  • R. Abraham
  • Genes & development
  • 2001
  • Corpus ID: 8243401
The genomes of eukaryotic cells are under continuous assault by environmental agents (e.g., UV light and reactive chemicals) as… 
Review
1996
Review
1996
Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly… 
Review
1996
Review
1996
Cell cycle checkpoints are regulatory pathways that control the order and timing of cell cycle transitions and ensure that… 
Review
1994
Review
1994
Multiple genetic changes occur during the evolution of normal cells into cancer cells. This evolution is facilitated in cancer… 
Highly Cited
1992
Highly Cited
1992
Cell cycle checkpoints appear to contribute to an increase in cell survival and a decrease in abnormal heritable genetic changes…