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CASP8AP2 wt Allele

Known as: RIP25, FLASH, CED-4 
Human CASP8AP2 wild-type allele is located in the vicinity of 6q15 and is approximately 45 kb in length. This allele, which encodes CASP8-associated… 
National Institutes of Health

Related topics

Related topics

5 relations
ApoptosisCASP8AP2 geneCaspase ActivationCaspase-Dependent Apoptosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Three-dimensional Models of NB-ARC Domains of Disease Resistance Proteins in Tomato, Arabidopsis, and Flax
Abstract Three dimensional models of NB-ARC domains in five different proteins were constructed based on the recently published… 
2002
2002
Differential requirement for Apaf1 and Bcl-XL in the regulation of programmed cell death during development
Differential requirement for Apaf1 and Bcl-X L in the regulation of programmed cell death during development 
2000
2000
Genetic analysis of the APAF1 gene in male germ cell tumors
Cytogenetic and molecular analyses have shown that the chromosome band 12q22 is recurrently deleted in male germ cell tumors… 
2000
2000
The Caenorhabditis elegans Sex Determination Protein FEM-1 Is a CED-3 Substrate That Associates with CED-4 and Mediates Apoptosis in Mammalian Cells*
Sex-specific elimination of cells by apoptosis plays a role in sex determination in Caenorhabditis elegans. Recently, a mammalian… 
1999
1999
Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation.
CED-4 protein plays an important role in the induction of programmed cell death in Caenorhabditis elegans through the activation… 
1999
1999
Oligomerized Ced-4 kills budding yeast through a caspase-independent mechanism.
In Caenorhabdtis elegans, Ced-3, Ced-4, and Ced-9 are components of a cell suicide program. Ced-4 facilitates the proteolytic… 
1998
1998
E1B 19,000-Molecular-Weight Protein Interacts with and Inhibits CED-4-Dependent, FLICE-Mediated Apoptosis
ABSTRACT Genetic studies of the nematode Caenorhabditis elegans(C. elegans) have identified several important components of the… 
Review
1998
Review
1998
Proteases, proteolysis, and apoptosis
Proteolytic cleavage of a limited number of cellular proteins is a central biochemical feature of apoptosis. Aspartate-specific… 
1997
1997
Programmed cell death: a missing link is found.
1997
1997
Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain?
Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain? 
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