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Caspase Activation

Known as: activation of caspase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process 
Caspase Activation involves induction of the activity of intracellular cysteine endopeptidase family members kept inactive by mitochondrial surface… 
National Institutes of Health

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APAF1 protein, humanActivated Caspase-3BBC3 geneBBC3 wt Allele

Broader (1)

Apoptosis

Papers overview

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2015
2015
Storage-dependent remodeling of the red blood cell membrane is associated with increased immunoglobulin G binding, lipid raft rearrangement, and caspase activation
2015
2015
Abstract 3343: Podophyllotoxin acetate (PA) enhancing γ-ionizing radiation-induced apoptosis via the ROS/p38/caspase pathway
To develop a new radiosensitizer candidate capable of increasing the efficiency of radiotherapy and to investigate the underlying… 
2014
2014
Resibufogenin inhibits the growth of human osteosarcoma MG-63 cells via mitochondrial pathway
Resibufogenin, a low molecular weight bufanolide steroid compound, is isolated from the secretion of Asiatic toad… 
2013
2013
Induction of G 2 / M arrest , caspase activation and apoptosis by a-santonin derivatives in HL-60 cells
Induction of G2/M arrest, caspase activation and apoptosis by a-santonin derivatives in HL-60 cells José Roberto Oliveira… 
2011
2011
Matador and the Regulation of cyclin E1 in Normal Human Placental Development and Placental Pathology
Preeclampsia and molar pregnancy are two devastating placental pathologies characterized by an immature proliferative trophoblast… 
2009
2009
The cyclin-dependent kinase inhibitor 5 , 6-dichloro-1-beta-D-ribofuranosylbenzimidazole induces nongenotoxic , DNA replication-independent apoptosis of normal and leukemic cells , regardless of…
The cyclin-dependent kinase inhibitor 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole induces nongenotoxic, DNA replication… 
2005
2005
p 53-Defective Tumors With a Functional Apoptosome-Mediated Pathway : A New Therapeutic Target
Background: Although cancer cells appear to maintain the machinery for intrinsic apoptosis, defects in the pathway develop during… 
2003
2003
INSULIN-PRODUCING HUMAN HEPATOCYTE CELLS DERIVED FROM MOUSE EMBRYONIC STEM CELLS INTO MICE CELL LINE FOR THE TEATMENT OF TYPE I DIABETES
withdrawn by the authors. University of Alabama at Birmingham, Birmingham, AL IHPI are susceptible to myriad insults during donor… 
2002
2002
Flavopiridol Potentiates STI 571-induced Mitochondrial Damage and Apoptosis in BCR-ABL-positive Human Leukemia Cells 1
Purpose: The goal of this study was to characterize interactions between the Bcr/Abl kinase inhibitor STI571 and the cyclin… 
2000
2000
Amyloid b-Peptide Effects on Synaptosomes from Apolipoprotein E-Deficient Mice *
Apolipoprotein E (apoE) is present in the brain and may contribute to neurophysiologic or neuropathologic events, depending on…