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BBC3 gene
Known as:
p53-UPREGULATED MODULATOR OF APOPTOSIS
, BBC3
, PUMA
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This gene plays a role in the regulation of apoptosis.
National Institutes of Health
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Related topics
Related topics
5 relations
Apoptosis
BBC3 protein, human
BBC3 wt Allele
Bcl-2-Binding Component 3
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
miR‐26b‐5p helps in EpCAM+cancer stem cells maintenance via HSC71/HSPA8 and augments malignant features in HCC
Ritu Khosla
,
Hamed Hemati
,
A. Rastogi
,
G. Ramakrishna
,
S. Sarin
,
N. Trehanpati
Liver international (Print)
2019
Corpus ID: 195807177
Targeting cancer stem cells (CSCs) in hepatocellular carcinoma (HCC) is difficult because of their similarities with normal stem…
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Highly Cited
2015
Highly Cited
2015
Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma.
Jian-jun Zhao
,
Zhang‐bo Chu
,
+15 authors
Ruben D Carrasco
Cancer Research
2015
Corpus ID: 17435077
Despite recent therapeutic advances that have doubled the median survival time of patients with multiple myeloma, intratumor…
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2015
2015
MiR-125b protects against ethanol-induced apoptosis in neural crest cells and mouse embryos by targeting Bak 1 and PUMA
Xiaopan Chen
,
Jie Liu
,
Wenke Feng
,
Xiaoyang Wu
,
Shao-yu Chen
Experimental Neurology
2015
Corpus ID: 24665997
2011
2011
BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina
J. Harder
,
R. Libby
Molecular Neurodegeneration
2011
Corpus ID: 3769309
BackgroundNaturally occurring apoptosis is a developmental process that shapes the retina by eliminating overproduced neurons. In…
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2011
2011
Melatonin sensitizes Caki renal cancer cells to kahweol‐induced apoptosis through CHOP‐mediated up‐regulation of PUMA
Hee Jung Um
,
Jong-Wook Park
,
T. Kwon
Journal of Pineal Research
2011
Corpus ID: 12536821
Abstract: Melatonin has recently gained attention as a regulator of biologic processes in addition to its effects on circadian…
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2008
2008
Tumor Suppressor Protein p53 Regulates Megakaryocytic Polyploidization and Apoptosis*
Peter G. Fuhrken
,
P. Apostolidis
,
S. Lindsey
,
W. Miller
,
E. Papoutsakis
Journal of Biological Chemistry
2008
Corpus ID: 25076552
The molecular mechanisms underlying differentiation of hematopoietic stem cells into megakaryocytes are poorly understood. Tumor…
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Highly Cited
2005
Highly Cited
2005
Therapeutic efficacy of PUMA for malignant glioma cells regardless of p53 status.
Hideaki Ito
,
T. Kanzawa
,
+6 authors
S. Kondo
Human Gene Therapy
2005
Corpus ID: 36193120
Replacement of the p53 tumor suppressor gene is a rational approach to the management of malignant gliomas because p53 is…
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2003
2003
Domestic Cats Infected with Lion or Puma Lentivirus Develop Anti-Feline Immunodeficiency Virus Immune Responses
S. Vandewoude
,
Catherine L Hageman
,
E. Hoover
Journal of Acquired Immune Deficiency Syndromes
2003
Corpus ID: 41361257
Attenuated live viral strains have afforded significant protection against virus challenge in HIV vaccine models. Although both…
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1997
1997
Growth of lion and puma lentiviruses in domestic cat cells and comparisons with FIV.
S. Vandewoude
,
Stephen J. O'Brien
,
+4 authors
Edward A. Hoover
Virology
1997
Corpus ID: 42750153
Feline immunodeficiency virus (FIV-Fca) is a lentivirus that causes gradual immunological deterioration in domestic cats…
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1997
1997
Infectivity of lion and puma lentiviruses for domestic cats.
S. Vandewoude
,
S. O’Brien
,
E. Hoover
Journal of General Virology
1997
Corpus ID: 16653506
Infection of domestic cats with feline immunodeficiency virus (FIV) causes progressive immunological deterioration similar to…
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