BBC3 gene

Known as: p53-UPREGULATED MODULATOR OF APOPTOSIS, BBC3, PUMA 
This gene plays a role in the regulation of apoptosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2018
0102020012018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Intestinal epithelial cell (IEC) apoptosis contributes to the development of ulcerative colitis (UC), an inflammatory bowel… (More)
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2011
2011
BACKGROUNDS & AIMS Saturated free fatty acids induce hepatocyte lipoapoptosis, a key pathologic feature of non-alcoholic… (More)
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2011
2011
BACKGROUND & AIMS Inflammatory bowel disease (IBD) is associated with increased apoptosis of intestinal epithelial cells (IECs… (More)
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2010
2010
EGFR and its constitutively activated variant EGFRvIII are linked to glioblastoma resistance to therapy, the mechanisms… (More)
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2010
2010
Acrolein, a highly reactive alpha,beta-unsaturated aldehyde, is an omnipresent environmental pollutant. Chronic and acute human… (More)
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2009
2009
In vivo administration of the mitochondrial inhibitor 3-nitropropionic acid (3-NP) produces striatal pathology mimicking… (More)
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2008
2008
p53-upregulated modulator of apoptosis (PUMA) plays an essential role in p53-dependent apoptosis following DNA damage. PUMA also… (More)
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Highly Cited
2007
Highly Cited
2007
p53-upregulated modulator of apoptosis (PUMA) is a BH3-only Bcl-2 family protein and an essential mediator of DNA damage-induced… (More)
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Highly Cited
2006
Highly Cited
2006
The p53-upregulated modulator of apoptosis (Puma), a BH3-only member of the Bcl-2 protein family, is required for p53-dependent… (More)
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2005
2005
Replacement of the p53 tumor suppressor gene is a rational approach to the management of malignant gliomas because p53 is… (More)
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