BBC3 wt Allele

Known as: PUMA, BCL2 Binding Component 3 wt Allele, FLJ42994 
Human BBC3 wild-type allele is located within 19q13.3-q13.4 and is approximately 12 kb in length. This allele, which encodes Bcl-2-binding component… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Wild-type p53 is a stress-responsive tumor suppressor and potent growth inhibitor. Genotoxic stresses (for example, ionizing and… (More)
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Highly Cited
2010
Highly Cited
2010
Synaptic activity promotes resistance to diverse apoptotic insults, the mechanism behind which is incompletely understood. We… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Puma (p53-upregulated modulator of apoptosis), a proapoptotic BH3-only member of the Bcl-2 protein family, has been… (More)
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Highly Cited
2007
Highly Cited
2007
Oxidative stress has been implicated as a key trigger of neuronal apoptosis in stroke and neurodegenerative conditions such as… (More)
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Highly Cited
2006
Highly Cited
2006
Nephrotoxicity is a major side effect of cisplatin, a widely used cancer therapy drug. Depending on its concentration, cisplatin… (More)
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Highly Cited
2005
Highly Cited
2005
Nicotinic acid (niacin) has long been used as an antidyslipidemic drug. Its special profile of actions, especially the rise in… (More)
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Highly Cited
2005
Highly Cited
2005
Numerous p53 target genes have been implicated in DNA damage-induced apoptosis signaling, but proapoptotic Bcl-2 (B-cell leukemia… (More)
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Highly Cited
2003
Highly Cited
2003
Apoptosis provoked by DNA damage requires the p53 tumor suppressor, but which of the many p53-regulated genes are required has… (More)
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1994
1994
The PUMA 560 robot is the white rat of robotics research i t has been studied and used in countless experiments over many years… (More)
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Highly Cited
1990
Highly Cited
1990
The puma (Felis concolor) has the most extensive range of any terrestrial mammal in the Western Hemisphere, covering over 100… (More)
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