CASP8AP2 gene

Known as: FLICE-ASSOCIATED HUGE PROTEIN, KIAA1315, CASP8AP2 
This gene is involved in apoptotic signaling.
National Institutes of Health

Papers overview

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Review
2001
Review
2001
The number and complexity of genes encoding nuclear lamina proteins has increased during metazoan evolution. Emerging evidence… (More)
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Highly Cited
1999
Highly Cited
1999
Here we identify a new gene, dark, which encodes a Drosophila homologue of mammalian Apaf-1 and Caenorhabditis elegans CED-4… (More)
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Highly Cited
1999
Highly Cited
1999
Caspase-9-mediated apoptosis (programmed cell death) plays a central role in the development and homeostasis of all multicellular… (More)
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Highly Cited
1998
Highly Cited
1998
Apoptosis is essential for the precise regulation of cellular homeostasis and development. The role in vivo of Apaf1, a mammalian… (More)
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Highly Cited
1998
Highly Cited
1998
The cytosolic protein APAF1, human homolog of C. elegans CED-4, participates in the CASPASE 9 (CASP9)-dependent activation of… (More)
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Highly Cited
1998
Highly Cited
1998
Bcl-2 family members either promote or repress programmed cell death. Bax, a death-promoting member, is a pore-forming… (More)
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Review
1998
Review
1998
Bcl-2 is the prototype of a class of oncogenes which regulates apoptosis. Bcl-2-related gene products with either death-promoting… (More)
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Highly Cited
1997
Highly Cited
1997
We report here the purification and cDNA cloning of Apaf-1, a novel 130 kd protein from HeLa cell cytosol that participates in… (More)
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Highly Cited
1997
Highly Cited
1997
Programmed cell death (apoptosis) is an evolutionarily conserved process used by multicellular organisms to eliminate cells that… (More)
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Review
1996
Review
1996
This inspiring book becomes one that is very booming. After published, this book can steal the market and book lovers to always… (More)
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