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CASP8AP2 gene

Known as: FLICE-ASSOCIATED HUGE PROTEIN, KIAA1315, CASP8AP2 
This gene is involved in apoptotic signaling.
National Institutes of Health

Related topics

Related topics

7 relations
ApoptosisCASP8-Associated Protein 2CASP8AP2 protein, humanCASP8AP2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Development of Two Murine Antibodies against Neospora caninum Using Phage Display Technology and Application on the Detection of N. caninum
Neosporosis, caused by an intracellular parasite, Neospora caninum, is an infectious disease primarily of cattle and dogs. It… 
2008
2008
Apoptosome assembly.
Review
2003
Review
2003
The importance of alternative splicing in the drug discovery process
Highly Cited
2000
Highly Cited
2000
Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors.
Demonstrating in vivo interaction of two important biomolecules and the relevance of the interaction to a biological process have… 
2000
2000
The Caenorhabditis elegans Sex Determination Protein FEM-1 Is a CED-3 Substrate That Associates with CED-4 and Mediates Apoptosis in Mammalian Cells*
Sex-specific elimination of cells by apoptosis plays a role in sex determination in Caenorhabditis elegans. Recently, a mammalian… 
Review
1999
Review
1999
Programmed cell death in the nematode C. elegans.
Programmed cell death is a common feature during animal development. In the nematode C. elegans, more than 12 genes have been… 
1999
1999
Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation.
CED-4 protein plays an important role in the induction of programmed cell death in Caenorhabditis elegans through the activation… 
1999
1999
Oligomerized Ced-4 kills budding yeast through a caspase-independent mechanism.
In Caenorhabdtis elegans, Ced-3, Ced-4, and Ced-9 are components of a cell suicide program. Ced-4 facilitates the proteolytic… 
Review
1998
Review
1998
Sealing one's fate: control of cell death in neurons
1998
1998
E1B 19,000-Molecular-Weight Protein Interacts with and Inhibits CED-4-Dependent, FLICE-Mediated Apoptosis
ABSTRACT Genetic studies of the nematode Caenorhabditis elegans(C. elegans) have identified several important components of the… 
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