CASP2 protein, human

OBJECTIVE Caspase-2 is an initiator caspase involved in multiple apoptotic pathways, particularly in response to specific… (More)

CASP2/caspase 2 plays a role in aging, neurodegeneration, and cancer. The contributions of CASP2 have been attributed to its… (More)

PS-341 (bortezomib) is a potent and reversible proteosome inhibitor that functions to degrade intracellular polyubiquitinated… (More)

AIM To study the distribution pattern of transcription factors NF-kappaB and AP-1 and their relations with the expression of… (More)

DNA damage induced by the cancer chemotherapeutic drug etoposide triggers the onset of a series of intracellular events… (More)

Continuous and long-lasting exposure to tert-butylhydroperoxide (t-BOOH) increased the number of apoptotic SH-SY5Y human… (More)

PURPOSE To investigate whether the neurohormone melatonin can prevent apoptosis caused by deprivation of oxygen, glucose, and… (More)

As part of the CASP2 protein structure prediction experiment, a set of numerical criteria were defined for the evaluation of "ab… (More)

COS cells are resistant to cell death induced either by interleukin-1beta-converting enzyme (*ICE) and ICE homolog (ICH-1L… (More)

We report here the isolation and characterization of Ich-1, a gene related to the C. elegans cell death gene ced-3 and the… (More)