Skip to search formSkip to main contentSkip to account menu

CASP2 gene

Known as: Caspase 2, Apoptosis-Related Cysteine Protease Gene, MGC2181, ICH1 
This gene is involved in either the promotion or inhibition of apoptosis depending on both the cell lineage and stage of development.
National Institutes of Health

Related topics

Related topics

6 relations
ApoptosisCASP2 protein, humanHydrolysisProteolysis

Narrower (1)

CASP2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Clinical characteristics of isolated clinic hypertension
Objective To analyze the clinical characteristics of patients with isolated clinic hypertension (ICH) compared with other… 
Highly Cited
2008
Highly Cited
2008
Role of Caspase 2 in Apoptotic Signaling in Primate and Murine Germ Cells1
Abstract This study investigates the role of caspase 2 in apoptotic signaling of nonhuman primate male germ cells triggered by… 
Review
2000
Review
2000
Life History and Developmental Processes in the Basidiomycete Coprinus cinereus
SUMMARY Coprinus cinereus has two main types of mycelia, the asexual monokaryon and the sexual dikaryon, formed by fusion of… 
Highly Cited
1998
Highly Cited
1998
Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury.
In the present study, we demonstrate that rat kidney contains caspase activity that was markedly inhibited by specific peptide… 
Highly Cited
1998
Highly Cited
1998
Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia.
Because caspase activation is an essential step in programmed cell death (apoptosis) and cytotoxic drug-induced apoptosis is… 
Highly Cited
1998
Highly Cited
1998
Caspase 2 and Caspase 3 Protein Levels as Predictors of Survival in Acute Myelogenous Leukemia
Because caspase activation is an essential step in programmed cell death (apoptosis) and cytotoxic drug-induced apoptosis is… 
Highly Cited
1997
Highly Cited
1997
Assessment of comparative modeling in CASP2
An assessment is presented for all submissions to the comparative modeling challenge in the 1996 Critical Assessment of Structure… 
Highly Cited
1997
Highly Cited
1997
CASP2 experiences with docking flexible ligands using FLEXX
We have applied our docking program FLEXX to all eight CASP2 targets involving protein complexes with small ligands. Of the seven… 
Highly Cited
1997
Highly Cited
1997
Homology modeling with internal coordinate mechanics: Deformation zone mapping and improvements of models via conformational search
Five models by homology containing insertions and deletions and ranging from 33% to 48% sequence identity to the known homologue… 
1997
1997
Analysis of comparative modeling predictions for CASP2 targets 1, 3, 9, and 17
Comparative modeling targets 1, 3, 9, and 17 were predicted by alignment of multiple sequences and structures, when available… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)