C3 gene

Known as: CPAMD1, ACYLATION-STIMULATING PROTEIN, C3 
This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Shiga toxin (Stx)-producing E.coli O157:H7 has become a global threat to public health; it is a primary cause of diarrhea… (More)
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Highly Cited
2010
Highly Cited
2010
The complement system as well as the coagulation system has fundamental clinical implications in the context of life-threatening… (More)
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Highly Cited
2008
Highly Cited
2008
The biochemical basis for complement acting directly on antigen-presenting cells to enhance their function in T-cell stimulation… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Biofilm formation is considered to be an important virulence factor of the opportunistic pathogen Staphylococcus… (More)
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Highly Cited
2007
Highly Cited
2007
Undesired complement activation is a major cause of tissue injury in various pathological conditions and contributes to several… (More)
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Highly Cited
2004
Highly Cited
2004
The mechanisms regulating the homing/mobilization of hematopoietic stem/progenitor cells (HSPCs) are not fully understood. In our… (More)
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Highly Cited
2003
Highly Cited
2003
Complement has recently been implicated in developmental pathways and noninflammatory processes. The expression of various… (More)
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Highly Cited
2002
Highly Cited
2002
In leukocytes, C3a and C5a cause chemotaxis in a G(i)-dependent, pertussis toxin (PT)-sensitive fashion. Because we found that… (More)
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Highly Cited
1995
Highly Cited
1995
Inflammatory action of the potent chemotaxin C5a has been well characterized on a variety of human cell types, including… (More)
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Highly Cited
1989
Highly Cited
1989
PURPOSE AND PATIENTS AND METHODS Both complement and contact system of coagulation have been implicated in the pathophysiology of… (More)
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