C3 DEFICIENCY

A rare genetic disorder with an autosomal recessive pattern of inheritance. It is caused by the ineffective or decreased biosynthesis of the third… (More)
National Institutes of Health

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Topic mentions per year

1975-2017
012319752017

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2017
2017
The complement cascade not only is an innate immune response that enables removal of pathogens but also plays an important role… (More)
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2014
2014
Human T helper type 1 (Th1) responses are essential in defense. Although T cell receptor (TCR) and co-stimulator engagement are… (More)
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2011
2011
Recent studies have demonstrated that complement contributes to the development of autoimmune diabetes. However, the mechanisms… (More)
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2005
2005
A case of inherited homozygous complement C3 deficiency (C3D) in a patient with systemic lupus erythematosus (SLE) and the… (More)
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2002
2002
C3 deficiency in humans is a rare disorder characterized by severe recurrent infections. We identified the mutations responsible… (More)
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2002
2002
Congenital deficiencies of complement system proteins are rare. A 4-year-old girl was admitted for meningitis. She had had… (More)
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1992
1992
Three families are described with complement component deficiencies. In one family, five children had C5 deficiency; in a second… (More)
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1990
1990
In experiments to ascertain the biochemical basis of a genetically determined deficiency of the third component of complement (C3… (More)
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1988
1988
A 10-year-old Laotian boy had homozygous deficiency of the third component of complement and recurrent bacterial infections… (More)
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1986
1986
A recently described genetically controlled C3 deficiency (C3D) in guinea pigs (GP) provided a unique model for studying the role… (More)
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