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C3 DEFICIENCY

A rare genetic disorder with an autosomal recessive pattern of inheritance. It is caused by the ineffective or decreased biosynthesis of the third… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
C3 deficiency protects against hippocampal neurodegeneration and cognitive decline in aged APP/PS1 mice despite abundant A… Expand
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2014
2014
Human T helper type 1 (Th1) responses are essential in defense. Although T cell receptor (TCR) and co-stimulator engagement are… Expand
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Highly Cited
2005
Highly Cited
2005
Our aim was to study whether the absence of apolipoprotein (apo) C3, a strong inhibitor of lipoprotein lipase (LPL), accelerates… Expand
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2005
2005
Three families are described with complement component deficiencies. In one family, five children had C5 deficiency; in a second… Expand
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2005
2005
A case of inherited homozygous complement C3 deficiency (C3D) in a patient with systemic lupus erythematosus (SLE) and the… Expand
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Highly Cited
2002
Highly Cited
2002
Background—The influence of complement activation on atherosclerosis is not well understood. The purpose of this study was to… Expand
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1994
1994
We recently described a case of hereditary complement C3 deficiency (C3D) in a New Zealand male who has a small amount of serum… Expand
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Review
1994
Review
1994
The third complement component (C3) is a multifunctional glycoprotein that interacts with numerous serum proteins, cell surface… Expand
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Review
1993
Review
1993
Inherited deficiency of complement C3 has been described in guinea pigs, dogs and 20 humans. Homozygous deficiency of C3 is… Expand
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1988
1988
A 10-year-old Laotian boy had homozygous deficiency of the third component of complement and recurrent bacterial infections… Expand
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