Complement 3

Known as: Complement, C3, Complement C3, Component 3, Complement 
A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Undesired complement activation is a major cause of tissue injury in various pathological conditions and contributes to several… (More)
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Highly Cited
2006
Highly Cited
2006
The intricate system of serum complement proteins provides resistance to infection. A pivotal step in the complement pathway is… (More)
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Highly Cited
2005
Highly Cited
2005
The complement system has been thought to originate exclusively in the deuterostomes. Here, we show that the central complement… (More)
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Highly Cited
2003
Highly Cited
2003
Some urodele amphibians possess the capacity to regenerate their body parts, including the limbs and the lens of the eye. The… (More)
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Highly Cited
2002
Highly Cited
2002
Accumulating evidence suggests that innate immunity interacts with the adaptive immune system to identify potentially harmful… (More)
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Highly Cited
2001
Highly Cited
2001
Recent studies implicate inflammation and complement mediated attack as early events in drusen biogenesis. The investigations… (More)
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Highly Cited
1998
Highly Cited
1998
Activation and covalent attachment of complement component C3 to pathogens is the key step in complement-mediated host defense… (More)
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Highly Cited
1996
Highly Cited
1996
We have screened a phage-displayed random peptide library for binding to C3b, the proteolytically activated form of complement… (More)
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Highly Cited
1985
Highly Cited
1985
The complete cDNA coding sequence and derived amino acid sequence of human complement component C3 are presented. The encoded… (More)
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Highly Cited
1983
Highly Cited
1983
Events that lead to phagocytosis of complement (C3)- or IgG-coated particles after their interaction with specific cell surface… (More)
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