Skip to search formSkip to main contentSkip to account menu

Bumetanide

Known as: 3-Butylamino-4-phenoxy-5-sulfamoylbenzoic acid, Bumetanidum, 3-Butylamino-4-phenoxy-5-sulfamoyl-benzoic acid 
A potent sulfamoylanthranilic acid derivative belonging to the class of loop diuretics. In the brain, bumetanide may prevent seizures in neonates by… 
National Institutes of Health

Related topics

Related topics

32 relations
AnuriaBumetanide 0.25 MG/ML Injectable SolutionBumetanide:MCnc:Pt:Ser/Plas:QnCongestive heart failure

Narrower (4)

BumexBurinexBurinex KFordiuran

Broader (3)

DiureticsSodium Potassium Chloride Symporter Inhibitorsbenzenesulfonamide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Bumetanide inhibits rapid kindling in neonatal rats
Purpose:  To examine the effects of bumetanide, a selective blocker of Na+‐K+‐2Cl− cotransporter (NKCC1), on hippocampal… 
Highly Cited
1992
Highly Cited
1992
Uneven distribution of intracellular Cl− in rat hippocampal neurons
Highly Cited
1986
Highly Cited
1986
Characterization of a cyclic AMP-activated Cl-transport pathway in the apical membrane of a human colonic epithelial cell line.
Highly Cited
1985
Highly Cited
1985
Ca2+-activated Na+ fluxes in human red cells. Amiloride sensitivity.
Highly Cited
1984
Highly Cited
1984
Regulation of Na/K/Cl cotransport in vascular smooth muscle cells.
Highly Cited
1984
Highly Cited
1984
Stimulation of K+ fluxes by diuretic drugs in human red cells.
Highly Cited
1984
Highly Cited
1984
Volume regulation of Chinese hamster ovary cells in anisoosmotic media.
Highly Cited
1982
Highly Cited
1982
(Na+,K+)-cotransport in the Madin-Darby canine kidney cell line. Kinetic characterization of the interaction between Na+ and K+.
Highly Cited
1979
Highly Cited
1979
Morphological alteration of the stria vascularis after administration of the diuretic bumetanide.
Chinchillas were given either a single injection of the diuretic bumetanide (18 mg/kg body weight) or saline-sodium hydroxide and… 
Highly Cited
1974
Highly Cited
1974
Renal action, therapeutic use, and pharmacokinetics of the diuretic bumetanide
The diuretic activity of bumetanide has been studied in 16 normal subiects and 40 hospitalized patients with fluid retention. The… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)