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Demonstration of a [K+,Cl-]-cotransport system in human red cells by its sensitivity to [(dihydroindenyl)oxy]alkanoic acids: regulation of cell swelling and distinction from the bumetanide-sensitive
A screening of several families of compounds on NEM-stimulated K+ efflux in human red cells allowed us to select a [(dihydroindenyl)oxy] alkanoic acid (DIOA) as the first potent inhibitor of this K+Expand
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Rat NKCC2/NKCC1 cotransporter selectivity for loop diuretic drugs
Abstract. It is generally assumed that bumetanide possesses some selectivity for the renal Na-K-Cl cotransporter NKCC2, although the results are scarce in the literature and comparisons were doneExpand
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Positive Regulatory Control Loop between Gut Leptin and Intestinal GLUT2/GLUT5 Transporters Links to Hepatic Metabolic Functions in Rodents
Background and Aims The small intestine is the major site of absorption of dietary sugars. The rate at which they enter and exit the intestine has a major effect on blood glucose homeostasis. In thisExpand
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Inheritance of abnormal erythrocyte cation transport in essential hypertension.
Net fluxes of sodium and potassium ions were determined in sodium-loaded, potassium-depleted erythrocytes from 370 white subjects, 194 of whom had essential hypertension or had been born to parentsExpand
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Abnormal Na+K+ cotransport function in a group of patients with essential hypertension
Abstract. In 50 normotensive controls, the increase in erythrocyte Na+ concentration up to 12.4 ± 2.0 mmol/l cells (mean ± SD) ensures half‐maximal stimulation of outward Na+K+ cotransport fluxes.Expand
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A genetic approach to the geography of hypertension : examination of Na+ - K+ cotransport in Ivory Coast Africans.
Outward Na+ - K+ cotransport in erythrocytes from essential hypertensive Caucasian subjects was found to be excessively low (Co -) compared to normotensives (Co +) carefully selected for theirExpand
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Abnormal erythrocyte Na+ K+ cotransport system, a proposed genetic marker of essential hypertension.
In erythrocytes, the extrusion of a cell sodium load is accomplished by the ouabain-sensitive sodium-potassium pump and by the furosemide-sensitive sodium-potassium cotransport, which operate againstExpand
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Green tea decoction improves glucose tolerance and reduces weight gain of rats fed normal and high-fat diet.
Green tea containing polyphenols exerts antidiabetic and antiobesity effects, but the mechanisms involved are not fully understood. In this study, we first analyzed and compared polyphenol compoundsExpand
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Reduced Intestinal Absorption of Dipeptides via PepT1 in Mice with Diet-induced Obesity Is Associated with Leptin Receptor Down-regulation*
Leptin is a major determinant of energy homeostasis, acting both centrally and in the gastrointestinal tract. We previously reported that acute leptin treatment enhances the absorption of di- andExpand
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The effect of cyclic AMP on Na+ and K+ transport systems in mouse macrophages
Exogenous cyclic AMP (cAMP) inhibits the Na+, K+-cotransport system and stimulates the Na+, K+-pump and Na+, Ca2+ exchange in mouse macrophages. These effects are enhanced by inhibition ofExpand
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