Benztropine

Known as: 3?-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane, 3alpha-Benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane, Benzatropina 
A centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
BACKGROUND The diagnosis of Parkinson disease is currently based on clinical evaluation. Functional neuroimaging using (123I… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE A functional polymorphism has been described in the promoter region of the gene (SLC6A4) coding for the serotonin… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Painful neuropathy is one of the most common long-term complications of diabetes mellitus and often proves difficult… (More)
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Highly Cited
2002
Highly Cited
2002
We investigated the microglial response to progressive dopamine neuron degeneration using in vivo positron emission tomography… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Although the popular drug 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") has been shown to damage brain… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) is a popular recreational drug that has been shown to damage brain… (More)
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Highly Cited
2000
Highly Cited
2000
Rapid eye movement (REM) sleep behaviour disorder (RBD) is characterized by complex behaviour during REM sleep. The aetiology of… (More)
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Highly Cited
1997
Highly Cited
1997
The metabolic activation resulting from direct dopaminergic stimulation can be detected using auto-radiography, positron emission… (More)
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1989
1989
This study assessed the efficacy of synthetic anticholinergic benztropine and incidence of side-effects in 20 developmentally… (More)
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Highly Cited
1987
Highly Cited
1987
A microdialysis/smallbore chromatographic system was used to monitor changes in extracellular dopamine concentration in the… (More)
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