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Benztropine

Known as: 3?-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane, 3alpha-Benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane, Benzatropina 
A centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake… 
National Institutes of Health

Related topics

Related topics

28 relations
2 ML benztropine mesylate 1 MG/ML Injection [Cogentin]Abnormalities, Drug-InducedBladder neck obstructionDrug Allergy

Broader (5)

Antiparkinson AgentsDopamine Uptake InhibitorsMuscarinic AntagonistsParasympatholytics

Narrower (4)

Cogentinbenztropine mesylatebenztropine mesylate 0.5 MG Oral Tabletbenztropine mesylate 2 MG Oral Tablet

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Dosimetry of an iodine-123-labeled tropane to image dopamine transporters.
UNLABELLED N-(3-Iodopropen-2-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropane (IPT) is an analog of cocaine that… 
Highly Cited
1988
Highly Cited
1988
Muscarinic M1, M2 receptor binding. Relationship with functional efficacy.
1988
1988
Dopamine-releasing action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) in the neostriatum of the rat as demonstrated in vivo by the push-pull perfusion…
1984
1984
Tolerance to an anticholinergic agent is paralleled by increased binding to muscarinic receptors in rat brain and increased behavioral response to a centrally active cholinomimetic.
Highly Cited
1981
Highly Cited
1981
Muscarinic cholinergic binding sites on intact human lymphocytes.
Highly Cited
1980
Highly Cited
1980
Release of dopamine from dissociated mesencephalic dopaminergic neurons in primary cultures in absence or presence of striatal target cells
Highly Cited
1979
Highly Cited
1979
Effects of the unilateral nigral application of dopaminergic drugs on the in vivo release of dopamine in the two caudate nuclei of the cat.
1979
1979
Circling behaviour induced by dopamine releasers and/or uptake inhibitors during degeneration of the nigrostriatal pathway.
Highly Cited
1974
Highly Cited
1974
Presence of dopaminergic terminals and absence of dopaminergic cell bodies in the cerebral cortex of the cat.
1973
1973
Antimuscarinic drugs--effect on brain acetylcholine and tremors in rats.
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