BECN1 gene

Known as: beclin 1, autophagy related, BECN1, VPS30 
This gene is involved in apoptosis regulation.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
INTRODUCTION Multiple gene expression based prognostic biomarkers have been repeatedly identified in gastric carcinoma. However… (More)
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Review
2014
Review
2014
The BECN1 gene encodes the Beclin-1 protein, which is a well-established regulator of the autophagic pathway. It is a mammalian… (More)
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2014
2014
The autophagy protein BECN1/Beclin 1 is known to play a central role in autophagosome formation and maturation. The results… (More)
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Highly Cited
2012
Highly Cited
2012
Macroautophagy (autophagy) is the major intracellular degradation pathway for long-lived proteins and organelles. It helps the… (More)
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Review
2010
Review
2010
Autophagy is an evolutionarily conserved lysosomal pathway for degrading cytoplasmic proteins, macromolecules, and organelles… (More)
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Highly Cited
2009
Highly Cited
2009
Recently, autophagy has emerged as a critical process in the control of T-cell homeostasis. Given the pivotal role of NF-kappaB… (More)
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Highly Cited
2008
Highly Cited
2008
To begin to understand the interplay between autophagy and the hypersensitive response (HR), a type of programmed cell death (PCD… (More)
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Highly Cited
2004
Highly Cited
2004
Macroautophagy is the major mechanism that eukaryotes use to recycle cellular components during stressful conditions. We have… (More)
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Highly Cited
2003
Highly Cited
2003
The biochemical properties of beclin 1 suggest a role in two fundamentally important cell biological pathways: autophagy and… (More)
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Highly Cited
1997
Highly Cited
1997
Mutations in the S. cerevisiae VPS29 and VPS30 genes lead to a selective protein sorting defect in which the vacuolar protein… (More)
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