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Autophagy

Known as: Macroautophagy, autophagy/autophagia, Autophagies, Cellular 
A normal process in which a cell destroys proteins and other substances in its cytoplasm (the fluid inside the cell membrane but outside the nucleus… 
National Institutes of Health

Related topics

Related topics

50 relations
ATG13 geneATG13 wt AlleleATG16L1 protein, humanATG16L1 wt Allele

Broader (2)

Phagocytosiscytotoxicity

Narrower (2)

Programmed Cell Death, Type IIcellular catabolic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib.
Highly Cited
2010
Highly Cited
2010
Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice
TRAF6 expression is enhanced during muscle atrophy and induces activation of signal transduction cascades that promote muscle… 
Review
2009
Review
2009
The role of autophagy in tumour development and cancer therapy
Autophagy is a catabolic membrane-trafficking process that leads to sequestration and degradation of intracellular material… 
Highly Cited
2008
Highly Cited
2008
Autophagy-mediated clearance of aggresomes is not a universal phenomenon.
Aggresomes are juxtanuclear inclusion bodies that have been proposed to act as staging grounds for the disposal of protein… 
Highly Cited
2007
Highly Cited
2007
Endoplasmic Reticulum Stress: A New Pathway to Induce Autophagy
Autophagy is a response to the stress of nutrient limitation in yeast, whereby cytosolic long-lived proteins and organelles are… 
Review
2006
Review
2006
Neuronal macroautophagy: from development to degeneration.
Highly Cited
2003
Highly Cited
2003
Emerging Role for Autophagy in the Removal of Aggresomes in Schwann Cells
The presence of protein aggregates in the nervous system is associated with various pathological conditions, yet their… 
Highly Cited
1996
Highly Cited
1996
Apoptotic changes occur in syncytiotrophoblast of human placental villi where fibrin type fibrinoid is deposited at discontinuities in the villous trophoblast.
Review
1988
Review
1988
Ubiquitin-mediated protein degradation.
Review
1981
Review
1981
Mechanisms of intralysosomal degradation with special reference to autophagocytosis and heterophagocytosis of cell organelles.
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