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ATG16L1 wt Allele

Known as: APG16L Beta, WDR30, APG16 Autophagy 16-Like (S. cerevisiae) Gene 
Human ATG16L1 wild-type allele is located in the vicinity of 2q37.1 and is approximately 86 kb in length. This allele, which encodes autophagy… 
National Institutes of Health

Related topics

Related topics

4 relations
2q37.1AutophagyAutophagy Regulation PathwayHomodimerization

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
HucMSC exosomes-delivered 14-3-3ζ enhanced autophagy via modulation of ATG16L in preventing cisplatin-induced acute kidney injury.
The clinical application of cisplatin is restricted by its side effects of nephrotoxicity. Human umbilical cord mesenchymal stem… 
Review
2015
Review
2015
Role of Inflammasomes in Intestinal Inflammation and Crohn's Disease
Abstract:Inflammasomes are multiprotein complexes that process procytokines into mature forms of interleukin 1&bgr; and… 
2015
2015
Annexin A2 promotes phagophore assembly by enhancing Atg16L+ vesicle biogenesis and homotypic fusion
Plasma membrane budding of Atg-16L-positive vesicles represents a very early event in the generation of the phagophore and in the… 
Highly Cited
2014
Highly Cited
2014
Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells.
Autophagy plays a pivotal role in cellular homeostasis and adaptation to adverse environments, although the regulation of this… 
Highly Cited
2014
Highly Cited
2014
Stearoyl-CoA Desaturase 1 Activity Is Required for Autophagosome Formation*
Background: Autophagosome membranes are believed to have a high content of unsaturated fatty acids, but the roles of unsaturated… 
2014
2014
Viability and gene expression responses to polymeric nanoparticles in human and rat cells
Applications of polymeric nanoparticles (NP) in medical fields are rapidly expanding. However, the influence of polymeric NP on… 
Highly Cited
2013
Highly Cited
2013
TMEM59 defines a novel ATG16L1‐binding motif that promotes local activation of LC3
Selective autophagy underlies many of the important physiological roles that autophagy plays in multicellular organisms, but the… 
Highly Cited
2013
Highly Cited
2013
Mechanical Unloading Activates FoxO3 to Trigger Bnip3‐Dependent Cardiomyocyte Atrophy
Background Mechanical assist device therapy has emerged recently as an important and rapidly expanding therapy in advanced heart… 
Review
2009
Review
2009
The late stages of autophagy: how does the end begin?
Autophagy is a catabolic cellular process involving dynamic membrane rearrangement. Here, we review the understanding of… 
2008
2008
Direct link between Atg protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals
Atg16L is a factor that is essential for elongation of the isolation membrane (also called phagophore), a precursor of the… 
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