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ATG16L1 wt Allele

Known as: APG16L Beta, WDR30, APG16 Autophagy 16-Like (S. cerevisiae) Gene 
Human ATG16L1 wild-type allele is located in the vicinity of 2q37.1 and is approximately 86 kb in length. This allele, which encodes autophagy… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
ABSTRACT A core set of autophagy proteins is required for gamma interferon (IFN-γ)-mediated clearance of Toxoplasma gondii in the… Expand
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Highly Cited
2013
Highly Cited
2013
Summary Macroautophagy is a bulk degradation process characterised by the formation of double-membrane vesicles, called… Expand
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Highly Cited
2011
Highly Cited
2011
Atg9 is a transmembrane protein essential for autophagy which cycles between the Golgi network, late endosomes and LC3-positive… Expand
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Highly Cited
2011
Highly Cited
2011
Breast cancer progression and metastasis are driven by complex and reciprocal interactions, between epithelial cancer cells and… Expand
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Highly Cited
2011
Highly Cited
2011
A large protein complex consisting of Atg5, Atg12 and Atg16L1 has recently been shown to be essential for the elongation of… Expand
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Highly Cited
2010
Highly Cited
2010
Autophagosome formation is a complex process that begins with the nucleation of a pre-autophagosomal structure (PAS) that expands… Expand
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Highly Cited
2010
Highly Cited
2010
Recently, using a co-culture system, we demonstrated that MCF7 epithelial cancer cells induce oxidative stress in adjacent cancer… Expand
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Highly Cited
2010
Highly Cited
2010
There is growing evidence that macroautophagic cargo is not limited to bulk cytosol in response to starvation and can occur… Expand
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Highly Cited
2008
Highly Cited
2008
Two ubiquitin-like molecules, Atg12 and LC3/Atg8, are involved in autophagosome biogenesis. Atg12 is conjugated to Atg5 and forms… Expand
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Highly Cited
2008
Highly Cited
2008
Macroautophagy is a mechanism of degradation of cytoplasmic components in all eukaryotic cells. In macroautophagy, cytoplasmic… Expand
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