Techniques for extraction and isolation of natural products: a comprehensive review
This paper intends to provide a comprehensive view of a variety of methods used in the extraction and isolation of natural products, presenting the advantage, disadvantage and practical examples of conventional and modern techniques involved in natural products research.
Antiviral flavonoids from the root bark of Morus alba L.
Autophagy and multidrug resistance in cancer
Multidrug resistance (MDR) occurs frequently after long-term chemotherapy, resulting in refractory cancer and tumor recurrence. Therefore, combatting MDR is an important issue. Autophagy, a…
Betulinic Acid and its Derivatives as Potential Antitumor Agents
- Dong-Mei Zhang, Hong‐Gui Xu, W. Ye
- Chemistry, BiologyMedicinal research reviews (Print)
- 1 November 2015
This review critically describes the recent research on isolation, synthesis, and derivatization of BA and its natural analogs betulin and 23‐hydroxybetulinic acid and focuses on the current knowledge of antitumor properties, combination treatments, and pharmacological mechanisms of these compounds.
Phenolic compounds from Origanum vulgare and their antioxidant and antiviral activities.
Characterization and Online Detection of Surfactin Isomers Based on HPLC-MSn Analyses and Their Inhibitory Effects on the Overproduction of Nitric Oxide and the Release of TNF-α and IL-6 in…
It was revealed that the surfactin isomers showed strong inhibitory properties on the overproduction of nitric oxide and the release of IL-6 on LPS-induced murine macrophage cell RAW264, which will be very helpful for the development of this novel kind of natural product as new anti-inflammatory agents.
New steroidal saponins and sterol glycosides from Paris polyphylla var. yunnanensis.
Four new steroidal saponins, pariposides A-D (1-4), and two new sterol glycosides, pariposides E-F (5-6), along with eight known steroidal saponins (7-14), two known sterol glycosides (15-16), and…
Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
The underlying antineoplastic mechanisms of arenobufagin that involve cross talk between apoptosis and autophagy via inhibition of the PI3K/Akt/mTOR pathway are elucidated.
Complete assignments of 1H and 13C NMR spectral data of nine surfactin isomers
- Jin-shan Tang, Hao Gao, X. Yao
- Chemistry, MathematicsMagnetic resonance in chemistry : MRC
- 1 September 2007
A new surfactin isomer was isolated from a mangrove bacteria strain ‘Bacillus sp’, and full assignments of 1H and 13C NMR spectral data were achieved for the first time by a combination of mass spectrometry and 1D and 2D NMR experiments.