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BECN1 protein, human

Known as: beclin 1 protein, human, GT197, Protein GT197 
A protein involved in autophagy (the process by which a cell destroys proteins and other substances in its cytoplasm). Beclin 1 is found at lower… 
National Institutes of Health

Related topics

Related topics

10 relations
Antiviral ResponseApoptosisAutophagyAutophagy Regulation Pathway

Broader (1)

Beclin-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
FOXO3 Inhibits Human Gastric Adenocarcinoma (AGS) Cell Growth by Promoting Autophagy in an Acidic Microenvironment
Background/Aims: Previous studies have shown that FOXO3, a member of the forkhead box O (FOXO) family, regulates autophagy in… 
2017
2017
Suppression of microRNA-384 enhances autophagy of airway smooth muscle cells in asthmatic mouse
Injury to airway smooth muscle (ASM) cells hallmarks the pathological progression of asthma, a chronic inflammatory airway… 
2017
2017
Autophagy can alleviate severe burn‐induced damage to the intestinal tract in mice
2015
2015
Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease during 24 Months of Follow-Up
Recent findings indicate that microglia in Alzheimer’s disease (AD) is senescent whereas peripheral blood mononuclear cells… 
2015
2015
Expression of Beclin-1 in the Microenvironment of Invasive Ductal Carcinoma of the Breast: Correlation with Prognosis and the Cancer-Stromal Interaction
We examined the pathobiological properties of beclin-1, which is a key regulator of autophagosome formation in invasive ductal… 
Review
2014
Review
2014
Unravelling the multifaceted roles of Atg proteins to improve cancer therapy
Autophagy follows a lysosomal degradation pathway in which a cell digests its own components. It is highly regulated by a limited… 
2013
2013
Herp depletion protects from protein aggregation by up-regulating autophagy.
2013
2013
The role of beclin-1 expression in patients with gastric cancer: a meta-analysis
Beclin-1 has been identified as a reliable biomarker in monitoring the prognosis for tumors. We carried out a meta-analysis… 
2012
2012
Changes in beclin-1 and micro-calpain expression in tri-ortho-cresyl phosphate-induced delayed neuropathy.
Highly Cited
2011
Highly Cited
2011
Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition
Purpose: Metastatic melanoma is characterized by extremely poor survival rates and hence novel therapies are urgently required… 
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