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BECN1 protein, human

Known as: beclin 1 protein, human, GT197, Protein GT197 
A protein involved in autophagy (the process by which a cell destroys proteins and other substances in its cytoplasm). Beclin 1 is found at lower… 
National Institutes of Health

Related topics

Related topics

10 relations
Antiviral ResponseApoptosisAutophagyAutophagy Regulation Pathway

Broader (1)

Beclin-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Emodin protects hyperglycemia-induced injury in PC-12 cells by up-regulation of miR-9
2016
2016
Macrophage autophagy regulated by miR-384-5p-mediated control of Beclin-1 plays a role in the development of atherosclerosis.
Macrophages play an essential and complicated role in the pathogenesis of atherosclerosis. However, the regulation of macrophage… 
2013
2013
Herp depletion protects from protein aggregation by up-regulating autophagy.
2013
2013
Autophagic Protein Beclin 1 Serves as an Independent Positive Prognostic Biomarker for Non-Small Cell Lung Cancer
Beclin 1, a key regulator of autophagy, has been found to be aberrantly expressed in a variety of human malignancies. Herein, we… 
2013
2013
Prognostic Significance of Beclin-1 Expression in Laryngeal Squamous Cell Carcinoma
Beclin-1 plays a critical role in the regulation of autophagy, apoptosis, differentiation and the development and progression of… 
2012
2012
Targeting Protective Autophagy Exacerbates UV-Triggered Apoptotic Cell Death
Autophagy is activated by various stresses, including DNA damage, and previous studies of DNA damage-induced autophagy have… 
2012
2012
High expression of the autophagy gene Beclin-1 is associated with favorable prognosis for salivary gland adenoid cystic carcinoma.
BACKGROUND Although autophagy is universally involved in tumorigenesis and tumor progression, the roles of autophagy and… 
2012
2012
Rapamycin treatment inhibits CHO cell death in a serum‐free suspension culture by autophagy induction
Rapamycin, a specific mTOR inhibitor, has been used as a chemical activator in autophagy research both in vitro and in vivo… 
Highly Cited
2011
Highly Cited
2011
Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition
Purpose: Metastatic melanoma is characterized by extremely poor survival rates and hence novel therapies are urgently required… 
2007
2007
Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells.
We have previously shown that oridonin isolated from Rabdosia rubescens augmented apoptosis while inhibiting autophagy within 24… 
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