Aldehyde Reductase

Known as: Alditol:NAD(P)+ 1-oxidoreductase, Reductase, Aldose, Aldose Reductase 
An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Pre-diabetes and diabetes are a global epidemic, and the associated neuropathic complications create a substantial burden on both… (More)
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Review
2005
Review
2005
Aldose reductase (AR) is widely expressed aldehyde-metabolizing enzyme. The reduction of glucose by the AR-catalyzed polyol… (More)
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Highly Cited
2003
Highly Cited
2003
The aldo-keto reductases (AKRs) are one of the three enzyme superfamilies that perform oxidoreduction on a wide variety of… (More)
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Highly Cited
2003
Highly Cited
2003
The 2-oxoaldehyde methylglyoxal (MeG) is the precursor to a number of the known advanced glycation endproducts (AGE) implicated… (More)
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Highly Cited
2001
Highly Cited
2001
Flavonoids belong to a group of polyphenolic compounds, which are classified as flavonols, flavonones, flavones, flavanols… (More)
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Review
2000
Review
2000
UNLABELLED BACKGROUND; In diabetic renal complications, hyperglycemia may cause damage at a cellular level in both glomerular and… (More)
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Highly Cited
1999
Highly Cited
1999
Hypertonicity (most often present as high salinity) is stressful to the cells of virtually all organisms. Cells survive in a… (More)
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Highly Cited
1998
Highly Cited
1998
We have identified a novel human protein that is highly homologous to aldose reductase (AR). This protein, which we called ARL-1… (More)
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Highly Cited
1997
Highly Cited
1997
The aldo-keto reductases (AKRs) represent a growing oxidoreductase superfamily. Forty proteins have been identified and… (More)
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Highly Cited
1989
Highly Cited
1989
Aldehyde reductase [EC 1.1.1.2] and aldose reductase [EC 1.1.1.21] are monomeric NADPH-dependent oxidoreductases having wide… (More)
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