• Publications
  • Influence
Recent progress in pharmacological research of propolis
TLDR
This review article compiles recent findings (since 1995) on the pharmacological properties of propolis focusing on its antihepatotoxic, antitumour, antioxidative, antimicrobial and antiinflammatory properties.
IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
TLDR
Results indicate that gomisin C is a mechanism-based inhibitor that not only competitively inhibits but irreversibly inactivates CYP3A4.
Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation.
TLDR
Investigation of the mechanism of action of arctigenin revealed that the compound blocked the activation of Akt induced by glucose starvation, which is a key process in the tolerance exhibited by cancer cells to glucose starvation.
Sulfation of environmental estrogens by cytosolic human sulfotransferases.
TLDR
The phenolic endocrine-disrupting chemicals, bisphenol A (BPA), 4-n-nonylphenol (NP), and 4-t-octyl phenol (t-OP), were used as substrates to investigate the possible participation of human SULTs in their metabolism for excretion.
Chemical constituents of Brazilian propolis and their cytotoxic activities.
The EtOAc-soluble fraction of the MeOH extract of propolis afforded a new prenylated chromane derivative, 3-hydroxy-2, 2-dimethyl-8-prenylchromane-6-propenoic acid (1), along with 22 known compounds,
Constituents of the Vietnamese medicinal plant Orthosiphon stamineus.
TLDR
All the isolated compounds were tested for their cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, and the new diterpenes, except for 4, and flavonoids showed cytot toxicity with an ED50 value between 10 and 90 microg/ml.
...
1
2
3
4
5
...