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Alcohol Oxidoreductases

Known as: Reductases, Carbonyl, alcohol oxidoreductase, Carbonyl Reductases 
A subclass of enzymes which includes all dehydrogenases acting on primary and secondary alcohols as well as hemiacetals. They are further classified… Expand
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (45)

2-dehydropantoate 2-reductase2-hydroxypropylthioethanesulfonate dehydrogenase, Xanthobacter3-dehydroquinate dehydratase-shikimate - NADP oxidoreductase3-ketodihydrosphingosine reductase
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AlcoholsIn BloodProcess of secretionantagonists & inhibitors
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Papers overview

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Highly Cited
2012
Highly Cited
2012
Effect of Graded Nrf2 Activation on Phase-I and -II Drug Metabolizing Enzymes and Transporters in Mouse Liver
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that induces a battery of cytoprotective genes in… Expand
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2011
2011
Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.
Polycyclic aromatic hydrocarbons (PAHs) are suspect human lung carcinogens and can be metabolically activated to remote quinones… Expand
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2010
2010
A rapid, reproducible, on-the-fly orthogonal array optimization method for targeted protein quantification by LC/MS and its application for accurate and sensitive quantification of carbonyl…
Liquid chromatography (LC)/mass spectrometry (MS) in selected-reactions-monitoring (SRM) mode provides a powerful tool for… Expand
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2008
2008
Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1
Monomeric carbonyl reductases (CBRs) are enzymes that catalyze the reduction of many endogenous and xenobiotic carbonyl compounds… Expand
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2008
2008
CBR1 and CBR3 pharmacogenetics and their influence on doxorubicin disposition in Asian breast cancer patients.
The present study aimed to identify polymorphic genes encoding carbonyl reductases (CBR1, CBR3) and investigate their influence… Expand
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Review
2004
Review
2004
Recent advances in the biocatalytic reduction of ketones and oxidation of sec-alcohols.
To improve the efficiency and applicability of biocatalytic redox-reactions for asymmetric ketone-reduction and enantioselective… Expand
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Highly Cited
2003
Highly Cited
2003
Construction and screening of metagenomic libraries derived from enrichment cultures: generation of a gene bank for genes conferring alcohol oxidoreductase activity on Escherichia coli.
Enrichment of microorganisms with special traits and the construction of metagenomic libraries by direct cloning of environmental… Expand
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2001
2001
Paclitaxel and docetaxel enhance the metabolism of doxorubicin to toxic species in human myocardium.
Doxorubicin cardiotoxicity is a multifactorial process in which the alcohol metabolite doxorubicinol mediates the transition from… Expand
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Review
1997
Review
1997
Human P450 metabolism of warfarin.
The anticoagulant drug warfarin occurs as a pair of enantiomers that are differentially metabolized by human cytochromes P450… Expand
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1978
1978
Heterogeneity of anthracycline antibiotic carbonyl reductases in mammalian livers.
Abstract The anticancer antibiotics, daunorubicin and adriamycin, are reduced to their corresponding alcohol and glycol… Expand
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